CAS 886465-70-9 Ridaifen-B - Analytical Products / Alfa Chemistry

CAT	AP886465709
CAS	886465-70-9
MDL Number	MFCD11114395
Molecular Weight	510.71
InChI Key	XQQWCGJGUHJSLR-UHFFFAOYSA-N

Description	≥98% (HPLC), white solid
Solubility	DMSO: ≥13 mg/mL; H2O: insoluble
Assay	≥98% (HPLC)
Form	white solid
Size	5MG, 25MG
Storage Conditions	2-8°C

1

Anti-proliferative Effect of ridaifen-B on Hepatoma Cells

Go Hasegawa, Kotomi Akatsuka, Keita Hiruma, Kayako Suda, Yumiko Yokoe, Akihito Mizusawa, Nozomi Ota, Natsumi Shibata, Kaho Tsuchiya, Moyuru Hayashi, Isamu Shiina, Motoyuki Shimonaka

Biomed Rep. 2018 Aug;9(2):175-180.

PMID: 30013780

1

Novel Ridaifen-B Structure Analog Induces Apoptosis and Autophagy Depending on Pyrrolidine Side Chain

Takumi Iwasawa, Takahisa Shinomiya, Nozomi Ota, Natsumi Shibata, Kenya Nakata, Isamu Shiina, Yukitoshi Nagahara

Biol Pharm Bull. 2019;42(3):401-410.

PMID: 30828072

1

Novel Tamoxifen Derivative Ridaifen-B Induces Bcl-2 Independent Autophagy Without Estrogen Receptor Involvement

Yukitoshi Nagahara, Midori Takeyoshi, Seiya Sakemoto, Isamu Shiina, Kenya Nakata, Keiko Fujimori, Yanwen Wang, Eri Umeda, Chihiro Watanabe, Shoko Uetake, Takao Yamori, Shingo Dan, Yoji Yoshimi, Takahisa Shinomiya, etc.

Biochem Biophys Res Commun. 2013 Jun 14;435(4):657-63.

PMID: 23688426

1

Ridaifen B, a Tamoxifen Derivative, Directly Binds to Grb10 Interacting GYF Protein 2

Senko Tsukuda, Tomoe Kusayanagi, Eri Umeda, Chihiro Watanabe, Yu-ta Tosaki, Shinji Kamisuki, Toshifumi Takeuchi, Yoichi Takakusagi, Isamu Shiina, Fumio Sugawara

Bioorg Med Chem. 2013 Jan 1;21(1):311-20.

PMID: 23199482

1

The tamoxifen derivative ridaifen-B is a high affinity selective CB 2 receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects

Lirit N Franks, Benjamin M Ford, Toshifumi Fujiwara, Haibo Zhao, Paul L Prather

Toxicol Appl Pharmacol. 2018 Aug 15;353:31-42.

PMID: 29906493

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