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RIPA-56

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For Research Use Only | Not For Clinical Use
CATAP1956370210
CAS1956370-21-0
Molecular Weight221.30
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Discovery of a Highly Potent, Selective, and Metabolically Stable Inhibitor of Receptor-Interacting Protein 1 (RIP1) for the Treatment of Systemic Inflammatory Response Syndrome

Yan Ren, Yaning Su, Liming Sun, Sudan He, Lingjun Meng, Daohong Liao, Xiao Liu, Yongfen Ma, Chunyan Liu, Sisi Li, Hanying Ruan, Xiaoguang Lei, Xiaodong Wang, Zhiyuan Zhang

J Med Chem. 2017 Feb 9;60(3):972-986.

PMID: 27992216

1

Inhibiting Necroptosis of Spermatogonial Stem Cell as a Novel Strategy for Male Fertility Preservation

Yun Xie, Haicheng Chen, Daosheng Luo, Xing Yang, Jiahui Yao, Chi Zhang, Linyan Lv, Zexin Guo, Cuncan Deng, Yanqing Li, Xiaoyan Liang, Chunhua Deng, Xiangzhou Sun, Guihua Liu

Stem Cells Dev. 2020 Apr 15;29(8):475-487.

PMID: 32024413

1

Inhibition of Receptor-Interacting Protein Kinase 1 Improves Experimental Non-Alcoholic Fatty Liver Disease

Amine Majdi, Lynda Aoudjehane, Vlad Ratziu, Tawhidul Islam, Marta B Afonso, Filomena Conti, Taïeb Mestiri, Marie Lagouge, Fabienne Foufelle, Florine Ballenghien, Tatiana Ledent, Marthe Moldes, Axelle Cadoret, etc.

J Hepatol. 2020 Apr;72(4):627-635.

PMID: 31760070

1

RIP1 Kinase Inhibitor Halts the Progression of an Immune-Induced Demyelination Disease at the Stage of Monocyte Elevation

Sitao Zhang, Yaning Su, Zhengxin Ying, Dejia Guo, Chenjie Pan, Jia Guo, Ziye Zou, Lei Wang, Ze Zhang, Zhaodi Jiang, Zhiyuan Zhang, Xiaodong Wang

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5675-5680.

PMID: 30837313

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