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RO-3306

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For Research Use Only | Not For Clinical Use
CATAP872573938
CAS872573-93-8
MDL NumberMFCD17392573
Molecular Weight351.45
InChI KeyXOLMRFUGOINFDQ-YBEGLDIGSA-N
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear
Assay≥98% (HPLC)
Coloroff-white to brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Specific Inhibitor of CDK1, RO-3306, Reversibly Arrests Meiosis During in Vitro Maturation of Porcine Oocytes

Woo-In Jang, Zi-Li Lin, Sung Hyun Lee, Suk Namgoong, Nam-Hyung Kim

Anim Reprod Sci. 2014 Jan 30;144(3-4):102-8.

PMID: 24374180

1

Cyclin-dependent Kinase 1 Inhibitor RO-3306 Enhances p53-mediated Bax Activation and Mitochondrial Apoptosis in AML

Kensuke Kojima, Masaya Shimanuki, Masato Shikami, Michael Andreeff, Hideki Nakakuma

Cancer Sci. 2009 Jun;100(6):1128-36.

PMID: 19385969

1

RO-3306 Prevents Postovulatory Aging-Mediated Spontaneous Exit From M-II Arrest in Rat Eggs Cultured in Vitro

Shilpa Prasad, Biplob Koch, Shail K Chaube

Biomed Pharmacother. 2016 Mar;78:216-225.

PMID: 26898445

1

Synchronization of HeLa Cells

Hoi Tang Ma, Randy Y C Poon

Methods Mol Biol. 2017;1524:189-201.

PMID: 27815904

1

Targeting CDK1 and MEK/ERK Overcomes Apoptotic Resistance in BRAF-Mutant Human Colorectal Cancer

Peng Zhang, Hisato Kawakami, Weizhen Liu, Xiangyu Zeng, Klaus Strebhardt, Kaixiong Tao, Shengbing Huang, Frank A Sinicrope

Mol Cancer Res. 2018 Mar;16(3):378-389.

PMID: 29233910

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