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RO5256390

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For Research Use Only | Not For Clinical Use
CATAP1043495960
CAS1043495-96-0
MDL NumberMFCD28405494
Molecular Weight218.29
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A New Perspective for Schizophrenia: TAAR1 Agonists Reveal Antipsychotic- And Antidepressant-Like Activity, Improve Cognition and Control Body Weight

F G Revel, J-L Moreau, B Pouzet, R Mory, A Bradaia, D Buchy, V Metzler, S Chaboz, K Groebke Zbinden, G Galley, R D Norcross, D Tuerck, A Bruns, S R Morairty, T S Kilduff, T L Wallace, C Risterucci, J G Wettstein, etc.

Mol Psychiatry. 2013 May;18(5):543-56.

PMID: 22641180

1

Activation of the Trace Amine-Associated Receptor 1 Prevents Relapse to Cocaine Seeking

Yui Pei, Jungah Lee, Damiana Leo, Raul R Gainetdinov, Marius C Hoener, Juan J Canales

Neuropsychopharmacology. 2014 Sep;39(10):2299-308.

PMID: 24722355

1

The Trace Amine-Associated Receptor 1 Agonist RO5256390 Blocks Compulsive, Binge-like Eating in Rats

Antonio Ferragud, Adam D Howell, Catherine F Moore, Tina L Ta, Marius C Hoener, Valentina Sabino, Pietro Cottone

Neuropsychopharmacology. 2017 Jun;42(7):1458-1470.

PMID: 27711047

1

Trace Amine Associated Receptor 1 (TAAR1) Modulation of Food Reward

Catherine F Moore, Valentina Sabino, Pietro Cottone

Front Pharmacol. 2018 Feb 27;9:129.

PMID: 29535626

1

Trace Amine-Associated Receptor 1 Agonists as Narcolepsy Therapeutics

Sarah W Black, Michael D Schwartz, Tsui-Ming Chen, Marius C Hoener, Thomas S Kilduff

Biol Psychiatry. 2017 Nov 1;82(9):623-633.

PMID: 27919403

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