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S 24795

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For Research Use Only | Not For Clinical Use
CATAP304679752
CAS304679-75-2
Structure
MDL NumberMFCD18086873
Molecular Weight418.07
InChI KeyLERUHBBUGAOYOD-UHFFFAOYSA-M
Description≥98% (HPLC)
SolubilityH2O: 1 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Dissociating Beta-Amyloid From Alpha 7 Nicotinic Acetylcholine Receptor by a Novel Therapeutic Agent, S 24795, Normalizes Alpha 7 Nicotinic Acetylcholine and NMDA Receptor Function in Alzheimer's Disease Brain

Hoau-Yan Wang, Andres Stucky, JingJing Liu, Changpeng Shen, Caryn Trocme-Thibierge, Philippe Morain

J Neurosci. 2009 Sep 2;29(35):10961-73.

PMID: 19726654

1

Improvement of Contextual Memory by S 24795 in Aged Mice: Comparison With Memantine

Daniel Beracochea, Aurelie Boucard, Caryn Trocme-Thibierge, Philippe Morain

Psychopharmacology (Berl). 2008 Mar;196(4):555-64.

PMID: 18034231

1

Partial Agonist and Neuromodulatory Activity of S 24795 for alpha7 nAChR Responses of Hippocampal Interneurons

Gretchen Lopez-Hernandez, Andon N Placzek, Jeffrey S Thinschmidt, Pierre Lestage, Caryn Trocme-Thibierge, Philippe Morain, Roger L Papke

Neuropharmacology. 2007 Jul;53(1):134-44.

PMID: 17544457

1

S 24795 Limits beta-amyloid-alpha7 Nicotinic Receptor Interaction and Reduces Alzheimer's Disease-Like Pathologies

Hoau-Yan Wang, Kalindi Bakshi, Changpeng Shen, Maya Frankfurt, Caryn Trocmé-Thibierge, Philippe Morain

Biol Psychiatry. 2010 Mar 15;67(6):522-30.

PMID: 19932469

1

The Partial alpha7 Nicotine Acetylcholine Receptor Agonist S 24795 Enhances Long-Term Potentiation at CA3-CA1 Synapses in the Adult Mouse Hippocampus

Laura Lagostena, Caryn Trocme-Thibierge, Philippe Morain, Enrico Cherubini

Neuropharmacology. 2008 Mar;54(4):676-85.

PMID: 18187166

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