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(S)-(+)-Camptothecin

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For Research Use Only | Not For Clinical Use
CATAP7689034-B
CAS7689-03-4
Structure
MDL NumberMFCD00081076
Molecular Weight348.35
InChI KeyVSJKWCGYPAHWDS-FQEVSTJZSA-N
REAXYS Number631069
Description≥90% (HPLC), powder
Solubilitychloroform/methanol (4:1): 5 mg/mL; enzyme | inhibits
Assay≥90% (HPLC)
Formpowder
MP260 °C (dec.) (lit.)
Size100MG, 250MG, 1G
Storage Conditions2-8°C
1

20-(S)-camptothecin Analogues as DNA Topoisomerase I Inhibitors: A QSAR Study

Corwin Hansch, Rajeshwar P Verma

ChemMedChem. 2007 Dec;2(12):1807-13.

PMID: 17886246

1

Antiangiogenic Effects of Camptothecin Analogues 9-amino-20(S)-camptothecin, Topotecan, and CPT-11 Studied in the Mouse Cornea Model

J J O'Leary, R L Shapiro, C J Ren, N Chuang, H W Cohen, M Potmesil

Clin Cancer Res. 1999 Jan;5(1):181-7.

PMID: 9918217

1

Degradation of camptothecin-20(S)-glycinate Ester Prodrug Under Physiological Conditions

Xinli Liu, Junhong Zhang, Lin Song, Bert C Lynn, Thomas G Burke

J Pharm Biomed Anal. 2004 Sep 3;35(5):1113-25.

PMID: 15336358

1

Formation of Nanoparticles by Cooperative Inclusion Between (S)-camptothecin-modified Dextrans and β-cyclodextrin Polymers

Thorbjørn Terndrup Nielsen, Catherine Amiel, Laurent Duroux, Kim Lambertsen Larsen, Lars Wagner Städe, Reinhard Wimmer, Véronique Wintgens

Beilstein J Org Chem. 2015 Jan 21;11:147-54.

PMID: 25670998

1

Identification of the Metabolites of 9-nitro-20(S)-camptothecin in Rats

Ke Li, Xiaoyan Chen, Dafang Zhong, Yan Li

Drug Metab Dispos. 2003 Jun;31(6):792-7.

PMID: 12756214

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