CAS 65567-34-2 (S)-(+)-Nirvanol - Analytical Products / Alfa Chemistry

CAT	AP65567342
CAS	65567-34-2
Structure
MDL Number	MFCD00272652
Molecular Weight	204.23
InChI Key	UDTWZFJEMMUFLC-NSHDSACASA-N

Solubility	DMF: soluble
Color	off-white
Size	5MG, 10MG
Storage Conditions	2-8°C

1

(+)-N-3-Benzyl-nirvanol and (-)-N-3-benzyl-phenobarbital: New Potent and Selective in Vitro Inhibitors of CYP2C19

Hisashi Suzuki, M Byron Kneller, Robert L Haining, William F Trager, Allan E Rettie

Drug Metab Dispos. 2002 Mar;30(3):235-9.

PMID: 11854139

1

Assessment of Urinary Mephenytoin Metrics to Phenotype for CYP2C19 and CYP2B6 Activity

Tobias Klaassen, Alexander Jetter, Dorota Tomalik-Scharte, Dirk Kasel, Julia Kirchheiner, Ulrich Jaehde, Uwe Fuhr

Eur J Clin Pharmacol. 2008 Apr;64(4):387-98.

PMID: 18071681

1

Enantiospecific Separation and Quantitation of Mephenytoin and Its Metabolites Nirvanol and 4'-hydroxymephenytoin in Human Plasma and Urine by Liquid chromatography/tandem Mass Spectrometry

Britt Jansson, Doaa Elsherbiny, Ulrika S H Simonsson

Rapid Commun Mass Spectrom. 2006;20(3):463-72.

PMID: 16395737

1

Human N-demethylation of (S)-mephenytoin by Cytochrome P450s 2C9 and 2B6

J W Ko, Z Desta, D A Flockhart

Drug Metab Dispos. 1998 Aug;26(8):775-8.

PMID: 9698292

1

Relation of in Vivo Drug Metabolism to Stereoselective Fetal Hydantoin Toxicology in Mouse: Evaluation of Mephenytoin and Its Metabolite, Nirvanol

P G Wells, A Küpfer, J A Lawson, R D Harbison

J Pharmacol Exp Ther. 1982 Apr;221(1):228-34.

PMID: 7062285

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