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S15535

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For Research Use Only | Not For Clinical Use
CATAP146998347
CAS146998-34-7
MDL NumberMFCD00911672
Molecular Weight336.43
InChI KeyQJPPEMXOOWNICQ-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: ~6 mg/mL; H2O: insoluble
Assay≥98% (HPLC)
Colorwhite
Formsolid
Size25MG
Storage Conditions2-8°C
1

Bidirectional Modulation of Classical Fear Conditioning in Mice by 5-HT(1A) Receptor Ligands With Contrasting Intrinsic Activities

Jiun Youn, Ilga Misane, Therese M Eriksson, Mark J Millan, Sven Ove Ogren, Matthijs Verhage, Oliver Stiedl

Neuropharmacology. Oct-Nov 2009;57(5-6):567-76.

PMID: 19607850

1

Serotonin 5-HT 1A Receptor Biased Agonists Display Differential Anxiolytic Activity in a Rat Social Interaction Model

Ronan Depoortère, Laurent Bardin, Mark A Varney, Adrian Newman-Tancredi

ACS Chem Neurosci. 2019 Jul 17;10(7):3101-3107.

PMID: 30929419

1

The 5HT(1A) Receptor Ligand, S15535, Antagonises G-protein Activation: A [35S]GTPgammaS and [3H]S15535 Autoradiography Study

A Newman-Tancredi, J Rivet, C Chaput, M Touzard, L Verrièle, M J Millan

Eur J Pharmacol. 1999 Nov 19;384(2-3):111-21.

PMID: 10611431

1

The Selective Serotonin (5-HT)1A Receptor Ligand, S15535, Displays Anxiolytic-Like Effects in the Social Interaction and Vogel Models and Suppresses Dialysate Levels of 5-HT in the Dorsal Hippocampus of Freely-Moving Rats. A Comparison With Other Anxiolytic Agents

A Dekeyne, M Brocco, A Adhumeau, A Gobert, M J Millan

Psychopharmacology (Berl). 2000 Sep;152(1):55-66.

PMID: 11041316

1

The serotonin1A Receptor Partial Agonist S15535 [4-(benzodioxan-5-yl)1-(indan-2-yl)piperazine] Enhances Cholinergic Transmission and Cognitive Function in Rodents: A Combined Neurochemical and Behavioral Analysis

Mark J Millan, Alain Gobert, Sylvain Roux, Roger Porsolt, Alfredo Meneses, Mirjana Carli, Benjamin Di Cara, Robert Jaffard, Jean-Michel Rivet, Pierre Lestage, Elisabeth Mocaer, Jean-Louis Peglion, Anne Dekeyne

J Pharmacol Exp Ther. 2004 Oct;311(1):190-203.

PMID: 15146031

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