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Safingol - CAS 15639-50-6

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For Research Use Only | Not For Clinical Use
CATAP15639506-B
CAS15639-50-6
Structure
Molecular Weight301.51
DescriptionA cell-permeable and reversible lyso-sphingolipid protein kinase C (PKC) inhibitor that competitively interacts at the regulatory phorbol binding domain of PKC.
Solubilityethanol: 10 mg/mL; DMSO: 5 mg/mL; methanol: 5 mg/mL
Assay≥98% (TLC)
Colorwhite
Formsolid
Size1MG
Storage Conditions-20C
1

Stress-Induced Changes in the Lipid Microenvironment of β-(1,3)-d-Glucan Synthase Cause Clinically Important Echinocandin Resistance in Aspergillus Fumigatus

Shruthi Satish, Cristina Jiménez-Ortigosa, Yanan Zhao, Min Hee Lee, Enriko Dolgov, Thomas Krüger, Steven Park, David W Denning, Olaf Kniemeyer, Axel A Brakhage, David S Perlin

mBio. 2019 Jun 4;10(3):e00779-19.

PMID: 31164462

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