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SAHA

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For Research Use Only | Not For Clinical Use
CATAP149647789
CAS149647-78-9
Structure
MDL NumberMFCD00945317
Molecular Weight264.32
InChI KeyWAEXFXRVDQXREF-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥15 mg/mL
Assay≥98% (HPLC)
Colorwhite to tan
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

BRD4 Inhibitor and Histone Deacetylase Inhibitor Synergistically Inhibit the Proliferation of Gallbladder Cancer in Vitro and in Vivo

Shilei Liu, Fengnan Li, Lijia Pan, Ziyi Yang, Yijun Shu, Wenjie Lv, Ping Dong, Wei Gong

Cancer Sci. 2019 Aug;110(8):2493-2506.

PMID: 31215139

1

Differential Mechanisms of Cell Death Induced by HDAC Inhibitor SAHA and MDM2 Inhibitor RG7388 in MCF-7 Cells

Umamaheswari Natarajan, Thiagarajan Venkatesan, Vijayaraghavan Radhakrishnan, Shila Samuel, Appu Rathinavelu

Cells. 2018 Dec 22;8(1):8.

PMID: 30583560

1

HDAC Inhibition Induces Autophagy and Mitochondrial Biogenesis to Maintain Mitochondrial Homeostasis During Cardiac ischemia/reperfusion Injury

Jing Yang, Jin He, Mahmoud Ismail, Sonja Tweeten, Fanfang Zeng, Ling Gao, Scott Ballinger, Martin Young, Sumanth D Prabhu, Glenn C Rowe, Jianyi Zhang, Lufang Zhou, Min Xie

J Mol Cell Cardiol. 2019 May;130:36-48.

PMID: 30880250

1

Histone Deacetylase Inhibition Blunts ischemia/reperfusion Injury by Inducing Cardiomyocyte Autophagy

Min Xie, Yongli Kong, Wei Tan, Herman May, Pavan K Battiprolu, Zully Pedrozo, Zhao V Wang, Cyndi Morales, Xiang Luo, Geoffrey Cho, Nan Jiang, Michael E Jessen, John J Warner, Sergio Lavandero, Thomas G Gillette, etc.

Circulation. 2014 Mar 11;129(10):1139-51.

PMID: 24396039

1

Late Autophagy Inhibitor Chloroquine Improves Efficacy of the Histone Deacetylase Inhibitor SAHA and Temozolomide in Gliomas

Rosângela Mayer Gonçalves, Jonathan Paulo Agnes, Marina Delgobo, Priscila Oliveira de Souza, Marcos P Thomé, Luana Heimfarth, Guido Lenz, José Cláudio Fonseca Moreira, Alfeu Zanotto-Filho

Biochem Pharmacol. 2019 May;163:440-450.

PMID: 30878553

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