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SANT-2

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For Research Use Only | Not For Clinical Use
CATAP329196487
CAS329196-48-7
Structure
Molecular Weight479.96
Description≥95% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥95% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Evidence for Allosteric Interactions of Antagonist Binding to the Smoothened Receptor

Cynthia M Rominger, Wei-Lin Tiger Bee, Robert A Copeland, Elizabeth A Davenport, Aidan Gilmartin, Richard Gontarek, Keith R Hornberger, Lorena A Kallal, Zhihong Lai, Kenneth Lawrie, Quinn Lu, Lynette McMillan, etc.

J Pharmacol Exp Ther. 2009 Jun;329(3):995-1005.

PMID: 19304771

1

Synthesis and Biological Evaluation of SANT-2 and Analogues as Inhibitors of the Hedgehog Signaling Pathway

Anita Büttner, Katrin Seifert, Thomas Cottin, Vasiliki Sarli, Lito Tzagkaroulaki, Stefan Scholz, Athanassios Giannis

Bioorg Med Chem. 2009 Jul 15;17(14):4943-54.

PMID: 19541490

1

Transcriptional Responses of Zebrafish Embryos Exposed to Potential Sonic Hedgehog Pathway Interfering Compounds Deviate From Expression Profiles of Cyclopamine

Anita Büttner, Wibke Busch, Nils Klüver, Athanassios Giannis, Stefan Scholz

Reprod Toxicol. 2012 Apr;33(2):254-63.

PMID: 22265815

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