CAS 152121-47-6 SB 203580 - Analytical Products / Alfa Chemistry

CAT	AP152121476-A
CAS	152121-47-6
MDL Number	MFCD00922198
Molecular Weight	377.43
InChI Key	CDMGBJANTYXAIV-UHFFFAOYSA-N

Description	solid, ≥98% (HPLC)
Solubility	DMSO: ≥20 mg/mL
Assay	≥98% (HPLC)
Color	white to off-white
Form	solid
Size	1MG
Storage Conditions	−20°C

1

Direct Inhibition of cyclooxygenase-1 and -2 by the Kinase Inhibitors SB 203580 and PD 98059. SB 203580 Also Inhibits Thromboxane Synthase

A G Börsch-Haubold, S Pasquet, S P Watson

J Biol Chem. 1998 Oct 30;273(44):28766-72.

PMID: 9786874

1

Effect of SB 203580 on the Activity of c-Raf in Vitro and in Vivo

C A Hall-Jackson, M Goedert, P Hedge, P Cohen

Oncogene. 1999 Mar 25;18(12):2047-54.

PMID: 10321729

1

Preclinical Pharmacokinetics of SB-203580, a Potent Inhibitor of p38 Mitogen-Activated Protein Kinase

K W Ward, J W Prokscht, L M Azzaranot, J A Mumawa, T J Roethke, G J Stelman, M J Walsh, K S Zeigler, J E McSurdy-Freed, J R Kehlert, J Chokshi, M A Levy, B R Smith

Xenobiotica. 2001 Nov;31(11):783-97.

PMID: 11765141

1

SB 203580 Inhibits p38 Mitogen-Activated Protein Kinase, Nitric Oxide Production, and Inducible Nitric Oxide Synthase in Bovine Cartilage-Derived Chondrocytes

A M Badger, M N Cook, M W Lark, T M Newman-Tarr, B A Swift, A H Nelson, F C Barone, S Kumar

J Immunol. 1998 Jul 1;161(1):467-73.

PMID: 9647257

1

SB 203580, an Inhibitor of p38 MAPK, Abolishes Infarct-Limiting Effect of Ischemic Preconditioning in Isolated Rabbit Hearts

A Nakano, M V Cohen, S Critz, J M Downey

Basic Res Cardiol. 2000 Dec;95(6):466-71.

PMID: 11192367

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