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SB 216763

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For Research Use Only | Not For Clinical Use
CATAP280744094-B
CAS280744-09-4
MDL NumberMFCD09753369
Molecular Weight371.22
InChI KeyJCSGFHVFHSKIJH-UHFFFAOYSA-N
Description>98% (HPLC)
SolubilityDMSO: soluble 20 mg/mL; H2O: insoluble
Assay>98% (HPLC)
Colororange
Size5MG, 25MG
Storage Conditions−20°C
1

Ankyrin-B Dysfunction Predisposes to Arrhythmogenic Cardiomyopathy and Is Amenable to Therapy

Jason D Roberts, Nathaniel P Murphy, Robert M Hamilton, Ellen R Lubbers, Cynthia A James, Crystal F Kline, Michael H Gollob, Andrew D Krahn, Amy C Sturm, Hassan Musa, Mona El-Refaey, Sara Koenig, Meriam Åström Aneq, etc.

J Clin Invest. 2019 Jul 2;129(8):3171-3184.

PMID: 31264976

1

Glycogen Synthase Kinase 3 (GSK3) Inhibitor, SB-216763, Promotes Pluripotency in Mouse Embryonic Stem Cells

Leslie A Kirby, Jason T Schott, Brenda L Noble, Daniel C Mendez, Paul S Caseley, Sarah C Peterson, Tyler J Routledge, Nilay V Patel

PLoS One. 2012;7(6):e39329.

PMID: 22745733

1

Inhibition of Glycogen Synthase kinase-3 by SB 216763 Affects Acquisition at Lower Doses Than Expression of Amphetamine-Conditioned Place Preference in Rats

Rebekah H Wickens, Susan E Quartarone, Richard J Beninger

Behav Pharmacol. 2017 Jun;28(4):262-271.

PMID: 27984209

1

SB-216763, a GSK-3β Inhibitor, Protects Against Aldosterone-Induced Cardiac, and Renal Injury by Activating Autophagy

Yi-De Zhang, Xiao-Jun Ding, Hou-Yong Dai, Wei-Sheng Peng, Nai-Feng Guo, Yuan Zhang, Qiao-Ling Zhou, Xiao-Lan Chen

J Cell Biochem. 2018 Jul;119(7):5934-5943.

PMID: 29600538

1

Synthesis and Initial in Vivo Studies With [(11)C]SB-216763: The First Radiolabeled Brain Penetrative Inhibitor of GSK-3

Lei Li, Xia Shao, Erin L Cole, Stephan A Ohnmacht, Valentina Ferrari, Young T Hong, David J Williamson, Tim D Fryer, Carole A Quesada, Phillip Sherman, Patrick J Riss, Peter J H Scott, Franklin I Aigbirhio

ACS Med Chem Lett. 2015 Mar 10;6(5):548-52.

PMID: 26005531

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