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SB 239063

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For Research Use Only | Not For Clinical Use
CATAP193551212-A
CAS193551-21-2
MDL NumberMFCD03792786
Molecular Weight368.40
InChI KeyZQUSFAUAYSEREK-WKILWMFISA-N
Description>98% (HPLC)
SolubilityDMSO: 11 mg/mL; H2O: insoluble
Assay>98% (HPLC)
Colorwhite
MP206-207.2 °C
Size5MG, 25MG
Storage Conditions2-8°C
1

Effect of the p38 MAPK Inhibitor SB-239063 on Lipopolysaccharide-induced Psychomotor Retardation and Peripheral Biomarker Alterations in Rats

Silvia Bison, Maria Razzoli, Roberto Arban, Francesca Michielin, Simone Bertani, Lucia Carboni

Eur J Pharmacol. 2011 Jul 1;661(1-3):49-56.

PMID: 21545800

1

SB 239063, a Novel p38 Inhibitor, Attenuates Early Neuronal Injury Following Ischemia

J J Legos, J A Erhardt, R F White, S C Lenhard, S Chandra, A A Parsons, R F Tuma, F C Barone

Brain Res. 2001 Feb 16;892(1):70-7.

PMID: 11172750

1

SB 239063, a p38 MAPK Inhibitor, Reduces Neutrophilia, Inflammatory Cytokines, MMP-9, and Fibrosis in Lung

D C Underwood, R R Osborn, S Bochnowicz, E F Webb, D J Rieman, J C Lee, A M Romanic, J L Adams, D W Hay, D E Griswold

Am J Physiol Lung Cell Mol Physiol. 2000 Nov;279(5):L895-902.

PMID: 11053025

1

SB 239063, a Potent p38 MAP Kinase Inhibitor, Reduces Inflammatory Cytokine Production, Airways Eosinophil Infiltration, and Persistence

D C Underwood, R R Osborn, C J Kotzer, J L Adams, J C Lee, E F Webb, D C Carpenter, S Bochnowicz, H C Thomas, D W Hay, D E Griswold

J Pharmacol Exp Ther. 2000 Apr;293(1):281-8.

PMID: 10734180

1

SB 239063, a Second-Generation p38 Mitogen-Activated Protein Kinase Inhibitor, Reduces Brain Injury and Neurological Deficits in Cerebral Focal Ischemia

F C Barone, E A Irving, A M Ray, J C Lee, S Kassis, S Kumar, A M Badger, R F White, M J McVey, J J Legos, J A Erhardt, A H Nelson, E H Ohlstein, A J Hunter, K Ward, B R Smith, J L Adams, A A Parsons

J Pharmacol Exp Ther. 2001 Feb;296(2):312-21.

PMID: 11160612

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