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SB-366791

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For Research Use Only | Not For Clinical Use
CATAP472981923
CAS472981-92-3
Structure
MDL NumberMFCD01033818
Molecular Weight287.74
InChI KeyRYAMDQKWNKKFHD-JXMROGBWSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: 5 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
1

Antinociceptive and Genotoxic Assessments of the Antagonist TRPV1 Receptor SB-366791 on Morphine-Induced Tolerance in Mice

Thiago Kastell Mazeto, Jaqueline Nascimento Picada, Áurea Pandolfo Correa, Isadora Nunes Rebelo, Magali Terra Ribeiro, Marcus Vinícius Gomez, Alessandra Hubner de Souza

Naunyn Schmiedebergs Arch Pharmacol. 2020 Mar;393(3):481-490.

PMID: 31655852

1

Identification and Characterisation of SB-366791, a Potent and Selective Vanilloid Receptor (VR1/TRPV1) Antagonist

M J Gunthorpe, H K Rami, J C Jerman, D Smart, C H Gill, E M Soffin, S Luis Hannan, S C Lappin, J Egerton, G D Smith, A Worby, L Howett, D Owen, S Nasir, C H Davies, M Thompson, P A Wyman, A D Randall, J B Davis

Neuropharmacology. 2004 Jan;46(1):133-49.

PMID: 14654105

1

Phoneutria Toxin PnTx3-5 Inhibits TRPV1 Channel With Antinociceptive Action in an Orofacial Pain Model

Elizete Maria Rita Pereira, Jéssica Mabelle Souza, Natália Virtude Carobin, Juliana Figueira Silva, Duana Carvalho Santos, Cláudio Antonio Silva Júnior, Nancy Scardua Binda, Márcia Helena Borges, Ronaldo Alves Pinto Nagem, etc.

Neuropharmacology. 2020 Jan 1;162:107826.

PMID: 31647972

1

The TRPV1 Channel Regulates Glucose Metabolism

Amanda J Page, George Hatzinikolas, Andrew D Vincent, Paul Cavuoto, Gary A Wittert

Am J Physiol Endocrinol Metab. 2019 Oct 1;317(4):E667-E676.

PMID: 31408376

1

TRPV1 Antagonist, SB-366791, Inhibits Glutamatergic Synaptic Transmission in Rat Spinal Dorsal Horn Following Peripheral Inflammation

Sarah C Lappin, Andrew D Randall, Martin J Gunthorpe, Valerie Morisset

Eur J Pharmacol. 2006 Jul 1;540(1-3):73-81.

PMID: 16737693

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