CAS 459429-39-1 SB 452533 - Analytical Products / Alfa Chemistry

CAT	AP459429391
CAS	459429-39-1
Structure
Molecular Weight	376.29

Description	≥98% (HPLC)
Solubility	DMSO: 20 mg/mL, clear
Assay	≥98% (HPLC)
Color	yellow to orange
Form	powder
Size	5MG, 25MG
Storage Conditions	room temp

1

Characterization of SB-705498, a Potent and Selective Vanilloid receptor-1 (VR1/TRPV1) Antagonist That Inhibits the Capsaicin-, Acid-, and Heat-Mediated Activation of the Receptor

Martin J Gunthorpe, Sara Luis Hannan, Darren Smart, Jeffrey C Jerman, Sandra Arpino, Graham D Smith, Stephen Brough, Jim Wright, Julie Egerton, Sarah C Lappin, Vicky A Holland, Kim Winborn, Mervyn Thompson, etc.

J Pharmacol Exp Ther. 2007 Jun;321(3):1183-92.

PMID: 17392405

1

Conservation of Functional and Pharmacological Properties in the Distantly Related Temperature Sensors TRVP1 and TRPM8

Annette Weil, Stephen E Moore, Nicola J Waite, Andrew Randall, Martin J Gunthorpe

Mol Pharmacol. 2005 Aug;68(2):518-27.

PMID: 15911692

1

Discovery of Small Molecule Antagonists of TRPV1

Harshad K Rami, Mervyn Thompson, Paul Wyman, Jeffrey C Jerman, Julie Egerton, Stephen Brough, Alexander J Stevens, Andrew D Randall, Darren Smart, Martin J Gunthorpe, John B Davis

Bioorg Med Chem Lett. 2004 Jul 16;14(14):3631-4.

PMID: 15203132

1

Measurement of Ensemble TRPV1 Ion Channel Currents Using Droplet Bilayers

Viksita Vijayvergiya, Shiv Acharya, Sidney P Wilson, Jacob J Schmidt

PLoS One. 2015 Oct 29;10(10):e0141366.

PMID: 26513481

1

Vanilloid-like Agents Inhibit Aggregation of Human Platelets

Safa Y Almaghrabi, Dominic P Geraghty, Kiran D K Ahuja, Murray J Adams

Thromb Res. 2014 Aug;134(2):412-7.

PMID: 24953906

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