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SB 657510

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For Research Use Only | Not For Clinical Use
CATAP474960446
CAS474960-44-6
Structure
Molecular Weight505.81
InChI KeyKQCZCINJGIRLCD-CYBMUJFWSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥30 mg/mL
Assay≥98% (HPLC)
Colorwhite to off-white
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Inhibitory Effect of an Urotensin II Receptor Antagonist on Proinflammatory Activation Induced by Urotensin II in Human Vascular Endothelial Cells

Sung Lyea Park, Bo Kyung Lee, Young-Ae Kim, Byung Ho Lee, Yi-Sook Jung

Biomol Ther (Seoul). 2013 Jul 30;21(4):277-83.

PMID: 24244812

1

Nonpeptidic urotensin-II Receptor Antagonists I: In Vitro Pharmacological Characterization of SB-706375

Stephen A Douglas, David J Behm, Nambi V Aiyar, Diane Naselsky, Jyoti Disa, David P Brooks, Eliot H Ohlstein, John G Gleason, Henry M Sarau, James J Foley, Peter T Buckley, Dulcie B Schmidt, William E Wixted, etc.

Br J Pharmacol. 2005 Jul;145(5):620-35.

PMID: 15852036

1

Retraction Statement: 'Urotensin II Inhibits Autophagy in Renal Tubular Epithelial Cells and Induces Extracellular Matrix Production in Early Diabetic mice' by Guan-Jong Chen, Fei Wu, Xin-Xin Pang, Ai-Hua Zhang, Jun-Bao Shi, Min Lu and Chao-Shu Tang

Guan-Jong Chen, Fei Wu, Xin-Xin Pang, Ai-Hua Zhang, Jun-Bao Shi, Min Lu, Chao-Shu Tang

J Diabetes Investig. 2017 Jul;8(4):629.

PMID: 27459313

1

RGS2 Regulates Urotensin II-induced Intracellular Ca2+ Elevation and Contraction in Glomerular Mesangial Cells

Adebowale Adebiyi

J Cell Physiol. 2014 Apr;229(4):502-11.

PMID: 24105430

1

Urotensin II Receptor Antagonism Confers Vasoprotective Effects in Diabetes Associated Atherosclerosis: Studies in Humans and in a Mouse Model of Diabetes

A M D Watson, M Olukman, C Koulis, Y Tu, D Samijono, D Yuen, C Lee, D J Behm, M E Cooper, K A M Jandeleit-Dahm, A C Calkin, T J Allen

Diabetologia. 2013 May;56(5):1155-65.

PMID: 23344731

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