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SB 699551 dihydrochloride

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For Research Use Only | Not For Clinical Use
CATAP864741957
CAS864741-95-7
Molecular Weight584.66
Description≥98% (HPLC)
SolubilityH2O: 1 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Effect of 5-HT5A Antagonists in Animal Models of Schizophrenia, Anxiety and Depression

Ferenc Kassai, Chantal Schlumberger, Rita Kedves, Malgorzata Pietraszek, Claudia Jatzke, Balázs Lendvai, István Gyertyán, Wojciech Danysz

Behav Pharmacol. 2012 Aug;23(4):397-406.

PMID: 22785385

1

SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4'-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide Dihydrochloride), a Novel 5-ht5A Receptor-Selective Antagonist, Enhances 5-HT Neuronal Function: Evidence for an Autoreceptor Role for the 5-ht5A Receptor in Guinea Pig Brain

David R Thomas, Ellen M Soffin, Claire Roberts, James N C Kew, Raul M de la Flor, Lee A Dawson, Victoria A Fry, Sara A Coggon, Stefania Faedo, Philip D Hayes, David F Corbett, Ceri H Davies, Jim J Hagan

Neuropharmacology. 2006 Sep;51(3):566-77.

PMID: 16846620

1

Spinal 5-HT₅A Receptors Mediate 5-HT-induced Antinociception in Several Pain Models in Rats

Enriqueta Muñoz-Islas, Guadalupe C Vidal-Cantú, Mariana Bravo-Hernández, Claudia Cervantes-Durán, Geovanna N Quiñonez-Bastidas, Jorge B Pineda-Farias, Paulino Barragán-Iglesias, Vinicio Granados-Soto

Pharmacol Biochem Behav. 2014 May;120:25-32.

PMID: 24517902

1

The 5-HT5A Receptor Regulates Excitability in the Auditory Startle Circuit: Functional Implications for Sensorimotor Gating

Paul C P Curtin, Violeta Medan, Heike Neumeister, Daniel R Bronson, Thomas Preuss

J Neurosci. 2013 Jun 12;33(24):10011-20.

PMID: 23761896

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