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SCH-28080

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For Research Use Only | Not For Clinical Use
CATAP76081986
CAS76081-98-6
Structure
MDL NumberMFCD00834620
Molecular Weight277.32
InChI KeyPYKJFEPAUKAXNN-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: soluble >10 mg/mL; H2O: insoluble
Assay≥98% (HPLC)
Colorwhite to light tan
Formsolid
Size10MG, 50MG
Storage Conditions−20°C
1

Mutational Analysis of Putative SCH 28080 Binding Sites of the Gastric H+,K+-ATPase

S Asano, S Matsuda, Y Tega, K Shimizu, S Sakamoto, N Takeguchi

J Biol Chem. 1997 Jul 11;272(28):17668-74.

PMID: 9211917

1

SCH 28080 Is a Lumenally Acting, K+-site Inhibitor of the Gastric (H+ + K+)-ATPase

D J Keeling, S M Laing, J Senn-Bilfinger

Biochem Pharmacol. 1988 Jun 1;37(11):2231-6.

PMID: 2837231

1

Sch-28080 Depletes Intracellular ATP Selectively in mIMCD-3 Cells

J Codina, J Cardwell, J J Gitomer, Y Cui, B C Kone, T D Dubose Jr

Am J Physiol Cell Physiol. 2000 Nov;279(5):C1319-26.

PMID: 11029278

1

Sch-28080 Inhibits Bafilomycin-Sensitive H+ Secretion in Turtle Bladder Independently of Luminal [K+]

O F Kohn, P P Mitchell, P R Steinmetz

Am J Physiol. 1993 Aug;265(2 Pt 2):F174-9.

PMID: 8368331

1

The H+/K+ ATPase Inhibitor SCH-28080 Inhibits Insulin Secretion and Induces Cell Death in INS-1E Rat Insulinoma Cells

Martin Jakab, Nina Ketterl, Johannes Fürst, Marlena Beyreis, Michael Kittl, Tobias Kiesslich, Cornelia Hauser-Kronberger, Martin Gaisberger, Markus Ritter

Cell Physiol Biochem. 2017;43(3):1037-1051.

PMID: 28968600

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