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SD-208

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For Research Use Only | Not For Clinical Use
CATAP627536098
CAS627536-09-8
Structure
MDL NumberMFCD11519969
Molecular Weight352.75
InChI KeyBERLXWPRSBJFHO-UHFFFAOYSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: >5 mg/mL
Assay≥98% (HPLC)
Coloroff-white to tan
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Evaluation of SD-208, a TGF-β-RI Kinase Inhibitor, as an Anticancer Agent in Retinoblastoma

Puran Fadakar, Abolfazl Akbari, Fariba Ghassemi, Gholam Reza Mobini, Masoumeh Mohebi, Manzar Bolhassani, Hoda Abed Khojasteh, Mansour Heidari

Acta Med Iran. 2016 Jun;54(6):352-8.

PMID: 27306340

1

Myofibroblast Modulation of Cardiac Myocyte Structure and Function

Chandan K Nagaraju, Eef Dries, Guillaume Gilbert, Mouna Abdesselem, Nan Wang, Matthew Amoni, Ronald B Driesen, Karin R Sipido

Sci Rep. 2019 Jun 20;9(1):8879.

PMID: 31222006

1

SD-208, a Novel Protein Kinase D Inhibitor, Blocks Prostate Cancer Cell Proliferation and Tumor Growth in Vivo by Inducing G2/M Cell Cycle Arrest

Manuj Tandon, Joseph M Salamoun, Evan J Carder, Elisa Farber, Shuping Xu, Fan Deng, Hua Tang, Peter Wipf, Q Jane Wang

PLoS One. 2015 Mar 6;10(3):e0119346.

PMID: 25747583

1

SD-208, a Novel Transforming Growth Factor Beta Receptor I Kinase Inhibitor, Inhibits Growth and Invasiveness and Enhances Immunogenicity of Murine and Human Glioma Cells in Vitro and in Vivo

Martin Uhl, Steffen Aulwurm, Jörg Wischhusen, Markus Weiler, Jing Ying Ma, Ramona Almirez, Ruban Mangadu, Yu-Wang Liu, Michael Platten, Ulrich Herrlinger, Alison Murphy, Darren H Wong, Wolfgang Wick, Linda S Higgins, etc.

Cancer Res. 2004 Nov 1;64(21):7954-61.

PMID: 15520202

1

TGF-beta-RI Kinase Inhibitor SD-208 Reduces the Development and Progression of Melanoma Bone Metastases

Khalid S Mohammad, Delphine Javelaud, Pierrick G J Fournier, Maria Niewolna, C Ryan McKenna, Xiang H Peng, Vu Duong, Lauren K Dunn, Alain Mauviel, Theresa A Guise

Cancer Res. 2011 Jan 1;71(1):175-84.

PMID: 21084275

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