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β-Secretase human

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For Research Use Only | Not For Clinical Use
CATIAR4248115
MDL NumberMFCD03702801
Descriptionrecombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), extracellular domain, ≥10,000 units/mg protein, ≥90% (SDS-PAGE), buffered aqueous solution
Assay≥90% (SDS-PAGE)
Formbuffered aqueous solution
Size50μG
Storage Conditions2-8°C
1

An Atomic Structure of Human γ-secretase

Xiao-Chen Bai, Chuangye Yan, Guanghui Yang, Peilong Lu, Dan Ma, Linfeng Sun, Rui Zhou, Sjors H W Scheres, Yigong Shi

Nature. 2015 Sep 10;525(7568):212-217.

PMID: 26280335

1

Recognition of the Amyloid Precursor Protein by Human γ-secretase

Rui Zhou, Guanghui Yang, Xuefei Guo, Qiang Zhou, Jianlin Lei, Yigong Shi

Science. 2019 Feb 15;363(6428):eaaw0930.

PMID: 30630874

1

Structural Basis of Notch Recognition by Human γ-secretase

Guanghui Yang, Rui Zhou, Qiang Zhou, Xuefei Guo, Chuangye Yan, Meng Ke, Jianlin Lei, Yigong Shi

Nature. 2019 Jan;565(7738):192-197.

PMID: 30598546

1

Targeting the β Secretase BACE1 for Alzheimer's Disease Therapy

Riqiang Yan, Robert Vassar

Lancet Neurol. 2014 Mar;13(3):319-29.

PMID: 24556009

1

Three-dimensional Structure of Human γ-secretase

Peilong Lu, Xiao-Chen Bai, Dan Ma, Tian Xie, Chuangye Yan, Linfeng Sun, Guanghui Yang, Yanyu Zhao, Rui Zhou, Sjors H W Scheres, Yigong Shi

Nature. 2014 Aug 14;512(7513):166-170.

PMID: 25043039

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