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SEW2871

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For Research Use Only | Not For Clinical Use
CATAP256414752
CAS256414-75-2
Structure
MDL NumberMFCD00096600
Molecular Weight440.36
InChI KeyOYMNPJXKQVTQTR-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: ≥10 mg/mL; H2O: insoluble
Assay≥98% (HPLC)
Colorwhite
Formsolid
MP94.5-95.3 °C
Size1MG, 5MG
Storage Conditions2-8°C
1

2-Cl-C.OXT-A Stimulates Contraction Through the Suppression of Phosphodiesterase Activity in Human Induced Pluripotent Stem Cell-Derived Cardiac Organoids

Takahiro Kitsuka, Manabu Itoh, Sojiro Amamoto, Ken-Ichi Arai, Junichi Oyama, Koichi Node, Shuji Toda, Shigeki Morita, Takahiro Nishida, Koichi Nakayama

PLoS One. 2019 Jul 11;14(7):e0213114.

PMID: 31295264

1

Oral Treatment With SEW2871, a sphingosine-1-phosphate Type 1 Receptor Agonist, Ameliorates Experimental Colitis in interleukin-10 Gene Deficient Mice

J Dong, H Wang, G Wu, J Zhao, L Zhang, L Zuo, W Zhu, J Gong, Y Li, L Gu, J Li

Clin Exp Immunol. 2014 Jul;177(1):94-101.

PMID: 24611843

1

SEW2871 Protects From Experimental Colitis Through Reduced Epithelial Cell Apoptosis and Improved Barrier Function in interleukin-10 Gene-Deficient Mice

Jianning Dong, Honggang Wang, Jie Zhao, Jing Sun, Tenghui Zhang, Lugen Zuo, Weiming Zhu, Jianfeng Gong, Yi Li, Lili Gu, Jieshou Li

Immunol Res. 2015 Mar;61(3):303-11.

PMID: 25588868

1

Sphingosine-1-Phosphate Receptor 1 Activation Enhances Leptomeningeal Collateral Development and Improves Outcome After Stroke in Mice

Eri Iwasawa, Satoru Ishibashi, Motohiro Suzuki, FuYing Li, Masahiko Ichijo, Kazunori Miki, Takanori Yokota

J Stroke Cerebrovasc Dis. 2018 May;27(5):1237-1251.

PMID: 29337049

1

Sphingosine-1-Phosphate Receptor-1 Agonist Sew2871 Causes Severe Cardiac Side Effects and Does Not Improve Microvascular Barrier Breakdown in Sepsis

Sven Flemming, Natalie Burkard, Michael Meir, Martin Alexander Schick, Christoph-Thomas Germer, Nicolas Schlegel

Shock. 2018 Jan;49(1):71-81.

PMID: 28538086

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