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SGC0946

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For Research Use Only | Not For Clinical Use
CATAP1561178173
CAS1561178-17-3
MDL NumberMFCD26523136
Molecular Weight618.57
InChI KeyIQCKJUKAQJINMK-HUBRGWSESA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Catalytic Site Remodelling of the DOT1L Methyltransferase by Selective Inhibitors

Wenyu Yu, Emma J Chory, Amy K Wernimont, Wolfram Tempel, Alex Scopton, Alexander Federation, Jason J Marineau, Jun Qi, Dalia Barsyte-Lovejoy, Joanna Yi, Richard Marcellus, Roxana E Iacob, John R Engen, etc.

Nat Commun. 2012;3:1288.

PMID: 23250418

1

Histone Methyltransferase DOT1L is Involved in Larval Molting and Second Stage Nymphal Feeding in Ornithodoros Moubata

Julia Gobl, Deepak Kumar Sinha, Radek Sima, Jan Perner, Petr Kopáček, James J Valdés, Ryan O M Rego, Alejandro Cabezas-Cruz

Vaccines (Basel). 2020 Apr 1;8(2):E157.

PMID: 32244625

1

Targeting Human SET1/MLL Family of Proteins

Masoud Vedadi, Levi Blazer, Mohammad S Eram, Dalia Barsyte-Lovejoy, Cheryl H Arrowsmith, Taraneh Hajian

Protein Sci. 2017 Apr;26(4):662-676.

PMID: 28160335

1

The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription

Matthew Wong, Andrew E L Tee, Giorgio Milazzo, Jessica L Bell, Rebecca C Poulos, Bernard Atmadibrata, Yuting Sun, Duohui Jing, Nicholas Ho, Dora Ling, Pei Yan Liu, Xu Dong Zhang, Stefan Hüttelmaier, Jason W H Wong, etc.

Cancer Res. 2017 May 1;77(9):2522-2533.

PMID: 28209620

1

Tri-methylation of H3K79 Is Decreased in TGF-β1-induced Epithelial-To-Mesenchymal Transition in Lung Cancer

Emilie Evanno, Julie Godet, Nathalie Piccirilli, Joëlle Guilhot, Serge Milin, Jean Marc Gombert, Benoit Fouchaq, Joëlle Roche

Clin Epigenetics. 2017 Aug 8;9:80.

PMID: 28804523

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