CAS 54795-58-3 Siastatin B - Analytical Products / Alfa Chemistry

CAT	AP54795583
CAS	54795-58-3
Structure
MDL Number	MFCD01631253
Molecular Weight	218.21
InChI Key	DQTKLICLJUKNCG-ZTYPAOSTSA-N

Description	lyophilized powder, from microbial
Solubility	H2O: 2.3 mL/vial (for a 10 mM solution)
Form	lyophilized powder
Size	5MG
Storage Conditions	−20°C

1

A Practical Synthesis From Siastatin B of (3S,4S,5R,6R)- 4,5-dihydroxy-6-(trifluoroacetamido)piperidine-3-carboxylic Acid Having Antimetastatic Activity in Mice

T Satoh, Y Nishimura, S Kondo, T Takeuchi

Carbohydr Res. 1996 Jun 5;286:173-8.

PMID: 8925513

1

Novel pH-dependent Regulation of Human Cytosolic Sialidase 2 (NEU2) Activities by Siastatin B and Structural Prediction of NEU2/siastatin B Complex

M Motiur Rahman, Takatsugu Hirokawa, Daisuke Tsuji, Jun Tsukimoto, Seiji Hitaoka, Tatsusada Yoshida, Hiroshi Chuman, Kohji Itoh

Biochem Biophys Rep. 2015 Sep 25;4:234-242.

PMID: 29124209

1

Synthesis and Activity of 1-N-iminosugar Inhibitors, Siastatin B Analogues for alpha-N-acetylgalactosaminidase and beta-N-acetylglucosaminidase

Y Nishimura, T Satoh, T Kudo, S Kondo, T Takeuchi

Bioorg Med Chem. 1996 Jan;4(1):91-6.

PMID: 8689244

1

Synthesis of the Sialidase Inhibitor Siastatin B

S Knapp, D Zhao

Org Lett. 2000 Dec 14;2(25):4037-40.

PMID: 11112637

1

Totally Synthetic Analogues of Siastatin B. III. Trifluoroacetamide Analogues Having Inhibitory Activity for Tumor Metastasis

Y Nishimura, T Kudo, S Kondo, T Takeuchi, T Tsuruoka, H Fukuyasu, S Shibahara

J Antibiot (Tokyo). 1994 Jan;47(1):101-7.

PMID: 8119851

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