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Silybin B

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For Research Use Only | Not For Clinical Use
CATAP142797340
CAS142797-34-0
MDL NumberMFCD18827498
Molecular Weight482.44
InChI KeySEBFKMXJBCUCAI-WAABAYLZSA-N
Descriptionanalytical standard
Assay≥98.0% (HPLC)
Formneat; gas chromatography (GC): suitable
Gradeanalytical standard
Impurity Content≤10.0% water; ≤3.0% residual solvents
Size5MG
1

A Comparison of the Diastereoisomers, Silybin A and Silybin B, on the Induction of Apoptosis in K562 Cells

Jiyong Zhang, Qiuying Luan, Yanze Liu, David Y W Lee, Zhao Wang

Nat Prod Commun. 2011 Nov;6(11):1653-6.

PMID: 22224281

1

Chemistry of Silybin

D Biedermann, E Vavříková, L Cvak, V Křen

Nat Prod Rep. 2014 Sep;31(9):1138-57.

PMID: 24977260

1

Enhanced Bioactivity of Silybin B Methylation Products

Arlene A Sy-Cordero, Tyler N Graf, Scott P Runyon, Mansukh C Wani, David J Kroll, Rajesh Agarwal, Scott J Brantley, Mary F Paine, Stephen J Polyak, Nicholas H Oberlies

Bioorg Med Chem. 2013 Feb 1;21(3):742-7.

PMID: 23260576

1

Relative Bioavailability of Silybin A and Silybin B From 2 Multiconstituent Dietary Supplement Formulations Containing Milk Thistle Extract: A Single-dose Study

Wen-Yi Li, Guo Yu, Renee M Hogan, Rajesh Mohandas, Reginald F Frye, Eric Gumpricht, John S Markowitz

Clin Ther. 2018 Jan;40(1):103-113.e1.

PMID: 29273470

1

The Effect of Milk Thistle (Silybum Marianum) and Its Main Flavonolignans on CYP2C8 Enzyme Activity in Human Liver Microsomes

Ahmed A Albassam, Reginald F Frye, John S Markowitz

Chem Biol Interact. 2017 Jun 1;271:24-29.

PMID: 28457856

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