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Sinefungin

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For Research Use Only | Not For Clinical Use
CATAP58944733
CAS58944-73-3
Structure
Molecular Weight381.39
InChI KeyLMXOHSDXUQEUSF-YECHIGJVSA-N
Description95% (HPLC), powder
SolubilityH2O: complete 20 mg/ml, clear, colorless to light yellow; H2O: soluble; enzyme | inhibits
Assay95% (HPLC)
Colorwhite to yellow
Formpowder
Size10MG
Storage Conditions2-8°C
1

Antiviral Effect of Sinefungin on in Vitro Growth of Feline Herpesvirus Type 1

Yudai Kuroda, Haruka Yamagata, Michiko Nemoto, Kenji Inagaki, Takashi Tamura, Ken Maeda

J Antibiot (Tokyo). 2019 Dec;72(12):981-985.

PMID: 31534199

1

Crystal Structure and Functional Analysis of the SARS-coronavirus RNA Cap 2'-O-methyltransferase nsp10/nsp16 Complex

Etienne Decroly, Claire Debarnot, François Ferron, Mickael Bouvet, Bruno Coutard, Isabelle Imbert, Laure Gluais, Nicolas Papageorgiou, Andrew Sharff, Gérard Bricogne, Miguel Ortiz-Lombardia, Julien Lescar, etc.

PLoS Pathog. 2011 May;7(5):e1002059.

PMID: 21637813

1

Genomewide Analysis of Mode of Action of the S-Adenosylmethionine Analogue Sinefungin in Leishmania infantum

Arijit Bhattacharya, Mansi Sharma, Charles Pakkinathan, Barry P Rosen, Philippe Leprohon, Marc Ouellette

mSystems. 2019 Oct 15;4(5):e00416-19.

PMID: 31615876

1

Inhibition of the H3K4 Methyltransferase SET7/9 Ameliorates Peritoneal Fibrosis

Ryo Tamura, Shigehiro Doi, Ayumu Nakashima, Kensuke Sasaki, Kazuya Maeda, Toshinori Ueno, Takao Masaki

PLoS One. 2018 May 3;13(5):e0196844.

PMID: 29723250

1

Mutational Analysis of Encephalitozoon Cuniculi mRNA Cap (guanine-N7) Methyltransferase, Structure of the Enzyme Bound to Sinefungin, and Evidence That Cap Methyltransferase Is the Target of Sinefungin's Antifungal Activity

Sushuang Zheng, Stéphane Hausmann, Quansheng Liu, Agnidipta Ghosh, Beate Schwer, Christopher D Lima, Stewart Shuman

J Biol Chem. 2006 Nov 24;281(47):35904-13.

PMID: 16971388

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