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Siomycin A

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For Research Use Only | Not For Clinical Use
CATAP12656096
CAS12656-09-6
Molecular Weight1648.84
Descriptionfrom Streptomyces sioyaensis, ≥98% (HPLC)
SolubilityDMSO: complete 10 mg/ml, clear, colorless to faintly yellow; DMSO: soluble
Assay≥98% (HPLC)
Size500μG
Storage Conditions−20°C
1

Effects and Mechanism of Siomycin A on the Growth and Apoptosis of MiaPaCa-2 Cancer Cells

Bin Wang, Wei Wang, Hao-Yi Meng, Jing Chen, Li-Jie Yuan

Oncol Lett. 2019 Sep;18(3):2869-2876.

PMID: 31452766

1

FOXM1 Is a Critical Driver of Lung Fibroblast Activation and Fibrogenesis

Loka R Penke, Jennifer M Speth, Vijaya L Dommeti, Eric S White, Ingrid L Bergin, Marc Peters-Golden

J Clin Invest. 2018 Jun 1;128(6):2389-2405.

PMID: 29733296

1

Siomycin A Induces Apoptosis in Human Lung Adenocarcinoma A549 Cells by Suppressing the Expression of FoxM1

Xuedan Guo, Aiping Liu, Hongxia Hua, Huifen Lu, Dandan Zhang, Yina Lin, Qing Sun, Xue Zhu, Guoxin Yan, Fan Zhao

Nat Prod Commun. 2015 Sep;10(9):1603-6.

PMID: 26594769

1

Siomycin A Targets Brain Tumor Stem Cells Partially Through a MELK-mediated Pathway

Ichiro Nakano, Kaushal Joshi, Koppany Visnyei, Bin Hu, Momoko Watanabe, Diana Lam, Eric Wexler, Kuniyasu Saigusa, Yuko Nakamura, Dan R Laks, Paul S Mischel, Mariano Viapiano, Harley I Kornblum

Neuro Oncol. 2011 Jun;13(6):622-34.

PMID: 21558073

1

Total Synthesis of Siomycin A: Completion of the Total Synthesis

Tomonori Mori, Shuhei Higashibayashi, Taiji Goto, Mitsunori Kohno, Yukiko Satouchi, Kazuyuki Shinko, Kengo Suzuki, Shunya Suzuki, Hiraku Tohmiya, Kimiko Hashimoto, Masaya Nakata

Chem Asian J. 2008 Jun 2;3(6):1013-25.

PMID: 18464235

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