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SKA-31

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For Research Use Only | Not For Clinical Use
CATAP40172654
CAS40172-65-4
Structure
MDL NumberMFCD00051329
Molecular Weight200.26
InChI KeyFECQXVPRUCCUIL-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥30 mg/mL
Assay≥98% (HPLC)
Formsolid
Size5MG, 25MG
Storage Conditions−20°C
1

Improvement of Endothelium-Dependent Vasodilations by SKA-31 and SKA-20, Activators of Small- And Intermediate-Conductance Ca2+ -Activated K+ -Channels

A-L Hasenau, G Nielsen, C Morisseau, B D Hammock, H Wulff, R Köhler

Acta Physiol (Oxf). 2011 Sep;203(1):117-26.

PMID: 21362152

1

Modulation of Cardiovascular Function in Primary Hypertension in Rat by SKA-31, an Activator of KCa2.x and KCa3.1 Channels

Monika Kloza, Marta Baranowska-Kuczko, Marek Toczek, Magdalena Kusaczuk, Olga Sadowska, Irena Kasacka, Hanna Kozłowska

Int J Mol Sci. 2019 Aug 23;20(17):4118.

PMID: 31450834

1

SKA-31, a Novel Activator of SK(Ca) and IK(Ca) Channels, Increases Coronary Flow in Male and Female Rat Hearts

Ramesh C Mishra, Darrell Belke, Heike Wulff, Andrew P Braun

Cardiovasc Res. 2013 Feb 1;97(2):339-48.

PMID: 23118129

1

SKA-31, an activator of Ca 2+-activated K + channels, improves cardiovascular function in aging

Cini Mathew John, Rayan Khaddaj Mallat, Ramesh C Mishra, Grace George, Vikrant Singh, Jeannine D Turnbull, Channakeshava S Umeshappa, Dylan J Kendrick, Taeyeob Kim, Fazlin M Fauzi, Frank Visser, Paul W M Fedak, etc.

Pharmacol Res. 2020 Jan;151:104539.

PMID: 31707036

1

SKA-31, an activator of endothelial Ca 2+-activated K + channels evokes robust vasodilation in rat mesenteric arteries

Rayan Khaddaj-Mallat, Cini Mathew John, Andrew P Braun

Eur J Pharmacol. 2018 Jul 15;831:60-67.

PMID: 29753043

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