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SKF-96365

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For Research Use Only | Not For Clinical Use
CATAP130495351
CAS130495-35-1
MDL NumberMFCD00236407
Molecular Weight402.91
InChI KeyFWLPKVQUECFKSW-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: >20 mg/mL; H2O: >20 mg/mL
Assay≥98% (HPLC)
Colorwhite
Formsolid
Size5MG
1

SKF-96365 Activates Cytoprotective Autophagy to Delay Apoptosis in Colorectal Cancer Cells Through Inhibition of the calcium/CaMKIIγ/AKT-mediated Pathway

Zhao Jing, Xinbing Sui, Junlin Yao, Jiansheng Xie, Liming Jiang, Yubin Zhou, Hongming Pan, Weidong Han

Cancer Lett. 2016 Mar 28;372(2):226-38.

PMID: 26803057

1

SKF-96365 Attenuates Toxin-Induced Neuronal Injury Through Opposite Regulatory Effects on Homer1a and Homer1b/c in Cultured Rat Mesencephalic Cells

Xuan Zeng, Zhi-Guo Pan, Yu Shao, Xiao-Na Wu, Shen-Xi Liu, Nan-Lin Li, Wei-Min Wang

Neurosci Lett. 2013 May 24;543:183-8.

PMID: 23567742

1

SKF-96365 Blocks Human ether-à-go-go-related Gene Potassium Channels Stably Expressed in HEK 293 Cells

Hui Liu, Lei Yang, Kui-Hao Chen, Hai-Ying Sun, Man-Wen Jin, Guo-Sheng Xiao, Yan Wang, Gui-Rong Li

Pharmacol Res. 2016 Feb;104:61-9.

PMID: 26689773

1

SKF-96365 Strongly Inhibits Voltage-Gated Sodium Current in Rat Ventricular Myocytes

Kui-Hao Chen, Hui Liu, Lei Yang, Man-Wen Jin, Gui-Rong Li

Pflugers Arch. 2015 Jun;467(6):1227-36.

PMID: 25017106

1

The TRPC Channel Blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na(+) /Ca(2+) Exchanger and Increasing Intracellular Ca(2+)

M Song, D Chen, S P Yu

Br J Pharmacol. 2014 Jul;171(14):3432-47.

PMID: 24641279

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