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SKI II

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For Research Use Only | Not For Clinical Use
CATAP312636161
CAS312636-16-1
Structure
MDL NumberMFCD00733553
Molecular Weight302.78
InChI KeyZFGXZJKLOFCECI-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: ≥20 mg/mL
Assay≥98% (HPLC)
Coloroff-white
Formsolid
Size10MG, 50MG
Storage Conditions2-8°C
1

A Sphingosine kinase-1 Inhibitor, SKI-II, Induces Growth Inhibition and Apoptosis in Human Gastric Cancer Cells

Pei-Hua Li, Jin-Xia Wu, Jun-Nian Zheng, Dong-Sheng Pei

Asian Pac J Cancer Prev. 2014;15(23):10381-5.

PMID: 25556479

1

SKI-II Reverses the Chemoresistance of SGC7901/DDP Gastric Cancer Cells

Ying Liu, Zuan Zhu, Hongxing Cai, Qinghua Liu, Honglian Zhou, Zhengqiu Zhu

Oncol Lett. 2014 Jul;8(1):367-373.

PMID: 24959278

1

SKI-II, an Inhibitor of Sphingosine Kinase, Ameliorates Antigen-Induced Bronchial Smooth Muscle Hyperresponsiveness, but Not Airway Inflammation, in Mice

Yoshihiko Chiba, Hiroki Takeuchi, Hiroyasu Sakai, Miwa Misawa

J Pharmacol Sci. 2010;114(3):304-10.

PMID: 20948165

1

SphK1 Inhibitor II (SKI-II) Inhibits Acute Myelogenous Leukemia Cell Growth in Vitro and in Vivo

Li Yang, Wei Weng, Zhi-Xin Sun, Xian-Jie Fu, Jun Ma, Wen-Fang Zhuang

Biochem Biophys Res Commun. 2015 May 15;460(4):903-8.

PMID: 25824043

1

SphK1 Inhibitor SKI II Inhibits the Proliferation of Human Hepatoma HepG2 Cells via the Wnt5A/β-catenin Signaling Pathway

Hong Liu, Cai-Xia Zhang, Yan Ma, Hong-Wei He, Jia-Ping Wang, Rong-Guang Shao

Life Sci. 2016 Apr 15;151:23-29.

PMID: 26944438

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