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SMBA1

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For Research Use Only | Not For Clinical Use
CATAP906440377
CAS906440-37-7
Molecular Weight315.32
InChI KeyPEYKRJBXACUOOB-WOJGMQOQSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells

Simona Daniele, Deborah Pietrobono, Barbara Costa, Mariateresa Giustiniano, Valeria La Pietra, Chiara Giacomelli, Giuseppe La Regina, Romano Silvestri, Sabrina Taliani, Maria Letizia Trincavelli, Federico Da Settimo, etc.

ACS Chem Neurosci. 2018 Jan 17;9(1):85-99.

PMID: 28368610

1

Modulation of Bax and mTOR for Cancer Therapeutics

Rui Li, Chunyong Ding, Jun Zhang, Maohua Xie, Dongkyoo Park, Ye Ding, Guo Chen, Guojing Zhang, Melissa Gilbert-Ross, Wei Zhou, Adam I Marcus, Shi-Yong Sun, Zhuo G Chen, Gabriel L Sica, Suresh S Ramalingam, etc.

Cancer Res. 2017 Jun 1;77(11):3001-3012.

PMID: 28381544

1

Selective BCL-XL Inhibition Promotes Apoptosis in Combination With MLN8237 in Medulloblastoma and Pediatric Glioblastoma Cells

Jane Levesley, Lynette Steele, Anke Brüning-Richardson, Adam Davison, Jia Zhou, Chunyong Ding, Sean Lawler, Susan C Short

Neuro Oncol. 2018 Jan 22;20(2):203-214.

PMID: 29016820

1

Small-molecule Bax Agonists for Cancer Therapy

Meiguo Xin, Rui Li, Maohua Xie, Dongkyoo Park, Taofeek K Owonikoko, Gabriel L Sica, Patrick E Corsino, Jia Zhou, Chunyong Ding, Mark A White, Andrew T Magis, Suresh S Ramalingam, Walter J Curran, Fadlo R Khuri, etc.

Nat Commun. 2014 Sep 17;5:4935.

PMID: 25230299

1

Structure-activity Relationship Studies on Bax Activator SMBA1 for the Treatment of ER-positive and Triple-Negative Breast Cancer

Gang Liu, Tao Yin, Hyejin Kim, Chunyong Ding, Zhuo Yu, Hong Wang, Haiying Chen, Ruping Yan, Eric A Wold, Hao Zou, Xi Liu, Ye Ding, Qiang Shen, Jia Zhou

Eur J Med Chem. 2019 Sep 15;178:589-605.

PMID: 31220676

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