Sphingosine kinase 2 Active human - Analytical Products / Alfa Chemistry

CAT

IAR42416150

Description	recombinant, expressed in baculovirus, ≥80% (SDS-PAGE)
Assay	≥80% (SDS-PAGE)
Form	aqueous solution
Size	20UG
Storage Conditions	−70°C

1

An Active Form of Sphingosine kinase-1 Is Released in the Extracellular Medium as Component of Membrane Vesicles Shed by Two Human Tumor Cell Lines

Salvatrice Rigogliuso, Chiara Donati, Donata Cassarà, Simona Taverna, Monica Salamone, Paola Bruni, Maria Letizia Vittorelli

J Oncol. 2010;2010:509329.

PMID: 20508814

1

FTY720/fingolimod Decreases Hepatic Steatosis and Expression of Fatty Acid Synthase in Diet-Induced Nonalcoholic Fatty Liver Disease in Mice

Timothy D Rohrbach, Amon Asgharpour, Melissa A Maczis, David Montefusco, L Ashley Cowart, Pierre Bedossa, Arun J Sanyal, Sarah Spiegel

J Lipid Res. 2019 Jul;60(7):1311-1322.

PMID: 31110049

1

FTY720/fingolimod Increases NPC1 and NPC2 Expression and Reduces Cholesterol and Sphingolipid Accumulation in Niemann-Pick Type C Mutant Fibroblasts

Jason Newton, Nitai C Hait, Michael Maceyka, Alexandria Colaco, Melissa Maczis, Christopher A Wassif, Antony Cougnoux, Forbes D Porter, Sheldon Milstien, Nicholas Platt, Frances M Platt, Sarah Spiegel

FASEB J. 2017 Apr;31(4):1719-1730.

PMID: 28082351

1

Sphingosine Kinase 2 Deficient Mice Exhibit Reduced Experimental Autoimmune Encephalomyelitis: Resistance to FTY720 but Not ST-968 Treatments

Faik Imeri, Stephanie Schwalm, Ruth Lyck, Aleksandra Zivkovic, Holger Stark, Britta Engelhardt, Josef Pfeilschifter, Andrea Huwiler

Neuropharmacology. 2016 Jun;105:341-350.

PMID: 26808312

1

Sphingosine kinase-1 Is Required for Toll Mediated Beta-Defensin 2 Induction in Human Oral Keratinocytes

Manjunatha R Benakanakere, Jiawei Zhao, Johnah C Galicia, Michael Martin, Denis F Kinane

PLoS One. 2010 Jul 9;5(7):e11512.

PMID: 20634980

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