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α-Spinasterol

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For Research Use Only | Not For Clinical Use
CATAP481185
CAS481-18-5
Structure
MDL NumberMFCD00200554
Molecular Weight412.69
Description≥98% (HPLC)
Solubilityethanol: 2 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

The Molecular Basis of Cytotoxicity of α-spinasterol From Ganoderma Resinaceum: Induction of Apoptosis and Overexpression of p53 in Breast and Ovarian Cancer Cell Lines

Nada K Sedky, Zaynab H El Gammal, Amir E Wahba, Eman Mosad, Zahraa Y Waly, Amira Ali El-Fallal, Reem K Arafa, Nagwa El-Badri

J Cell Biochem. 2018 May;119(5):3892-3902.

PMID: 29143969

1

The Potential of α-Spinasterol to Mimic the Membrane Properties of Natural Cholesterol

Ivan Haralampiev, Holger A Scheidt, Daniel Huster, Peter Müller

Molecules. 2017 Aug 22;22(8):1390.

PMID: 28829376

1

α-Spinasterol From Melandrium Firmum Attenuates Benign Prostatic Hyperplasia in a Rat Model

Mee-Young Lee, In-Sik Shin, Hwangbo Kyoung, Chang-Seob Seo, Jong-Keun Son, Hyeun-Kyoo Shin

Mol Med Rep. 2014 Jun;9(6):2362-6.

PMID: 24682042

1

α-Spinasterol, a TRPV1 Receptor Antagonist, Elevates the Seizure Threshold in Three Acute Seizure Tests in Mice

Katarzyna Socała, Dorota Nieoczym, Mateusz Pieróg, Piotr Wlaź

J Neural Transm (Vienna). 2015 Sep;122(9):1239-47.

PMID: 25764210

1

α-Spinasterol: A COX Inhibitor and a Transient Receptor Potential Vanilloid 1 Antagonist Presents an Antinociceptive Effect in Clinically Relevant Models of Pain in Mice

Indiara Brusco, Camila Camponogara, Fabiano Barbosa Carvalho, Maria Rosa Chitolina Schetinger, Mauro Schneider Oliveira, Gabriela Trevisan, Juliano Ferreira, Sara Marchesan Oliveira

Br J Pharmacol. 2017 Dec;174(23):4247-4262.

PMID: 28849589

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