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SR 27417

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For Research Use Only | Not For Clinical Use
CATAP136468365
CAS136468-36-5
Structure
MDL NumberMFCD00904759
Molecular Weight464.71
InChI KeyVVBFISAUNSXQGZ-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL (clear solution, warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Binding of [3H]SR 27417, a Novel Platelet-Activating Factor (PAF) Receptor Antagonist, to Rabbit and Human Platelets and Polymorphonuclear Leukocytes

J M Herbert, M C Laplace, J P Maffrand

Biochem Pharmacol. 1993 Jan 7;45(1):51-8.

PMID: 8381007

1

Biochemical and Pharmacological Activities of SR 27417, a Highly Potent, Long-Acting Platelet-Activating Factor Receptor Antagonist

J M Herbert, A Bernat, G Valette, V Gigo, A Lale, M C LaPlace, L Lespy, P Savi, J P Maffrand, G Le Fur

J Pharmacol Exp Ther. 1991 Oct;259(1):44-51.

PMID: 1656029

1

Effect of SR 27417, a Novel PAF Antagonist on Antigen-Induced Hypotension in the Rat

J M Herbert, A Bernat, E Tibiriça

J Lipid Mediat Cell Signal. 1997 Jan;15(2):115-23.

PMID: 9034959

1

In Vitro Inhibitory Effect of SR 27417, a Potent Platelet-Activating Factor (PAF) Receptor Antagonist, on the PAF-induced Bovine Platelet Aggregation

M Bastos da Silva, A Delaunois, P Gustin, J M Godeau, P Lekeux

Vet Res. Mar-Apr 2000;31(2):267-72.

PMID: 10779205

1

Structural Basis for Signal Recognition and Transduction by Platelet-Activating-Factor Receptor

Can Cao, Qiuxiang Tan, Chanjuan Xu, Lingli He, Linlin Yang, Ye Zhou, Yiwei Zhou, Anna Qiao, Minmin Lu, Cuiying Yi, Gye Won Han, Xianping Wang, Xuemei Li, Huaiyu Yang, Zihe Rao, Hualiang Jiang, Yongfang Zhao, etc.

Nat Struct Mol Biol. 2018 Jun;25(6):488-495.

PMID: 29808000

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