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SR9238

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For Research Use Only | Not For Clinical Use
CATAP1416153622
CAS1416153-62-2
Molecular Weight595.73
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Liver-Selective LXR Inverse Agonist That Suppresses Hepatic Steatosis

Kristine Griffett, Laura A Solt, Bahaa El-Dien M El-Gendy, Theodore M Kamenecka, Thomas P Burris

ACS Chem Biol. 2013 Mar 15;8(3):559-67.

PMID: 23237488

1

Activation of the Liver X Receptor Pathway Inhibits HBV Replication in Primary Human Hepatocytes

Jing Zeng, Daitze Wu, Hui Hu, John A T Young, Zhipeng Yan, Lu Gao

Hepatology. 2020 Mar 7.

PMID: 32145089

1

Inhibition of Hepatotoxicity by a LXR Inverse Agonist in a Model of Alcoholic Liver Disease

Monideepa Sengupta, Kristine Griffett, Colin A Flaveny, Thomas P Burris

ACS Pharmacol Transl Sci. 2018 Sep 14;1(1):50-60.

PMID: 31696159

1

Screening of House Dust from Chinese Homes for Chemicals with Liver X Receptors Binding Activities and Characterization of Atherosclerotic Activity Using an in Vitro Macrophage Cell Line and ApoE-/- Mice

Wenxin Hu, Yingting Jia, Qiyue Kang, Hui Peng, Haojia Ma, Shiyi Zhang, Youhei Hiromori, Tomoki Kimura, Tsuyoshi Nakanishi, Lemin Zheng, Yifu Qiu, Zhaobin Zhang, Yi Wan, Jianying Hu

Environ Health Perspect. 2019 Nov;127(11):117003.

PMID: 31724879

1

The LXR Inverse Agonist SR9238 Suppresses Fibrosis in a Model of Non-Alcoholic Steatohepatitis

Kristine Griffett, Ryan D Welch, Colin A Flaveny, Grant R Kolar, Brent A Neuschwander-Tetri, Thomas P Burris

Mol Metab. 2015 Feb 9;4(4):353-7.

PMID: 25830098

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