CAS 459848-35-2 Src Kinase Inhibitor II - CAS 459848-35-2 - Analytical Products / Alfa Chemistry

CAT	AP459848352
CAS	459848-35-2
Molecular Weight	420.48

Description	The Src Kinase Inhibitor II, also referenced under CAS 459848-35-2, controls the biological activity of Src Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Solubility	DMSO: 20 mg/mL
Assay	≥97% (HPLC)
Color	pale orange
Form	solid; protect from light
Size	5MG
Storage Conditions	+2C to +8C

1

An Endogenous Inhibitor of Focal Adhesion Kinase Blocks Rac1/JNK but Not Ras/ERK-dependent Signaling in Vascular Smooth Muscle Cells

Liisa J Sundberg, Lisa M Galante, Heather M Bill, Christopher P Mack, Joan M Taylor

J Biol Chem. 2003 Aug 8;278(32):29783-91.

PMID: 12782622

1

Neoadjuvant Dasatinib for Muscle-Invasive Bladder Cancer With Tissue Analysis of Biologic Activity

Noah M Hahn, Beatrice S Knudsen, Siamak Daneshmand, Michael O Koch, Richard Bihrle, Richard S Foster, Thomas A Gardner, Liang Cheng, Ziyue Liu, Timothy Breen, Mark T Fleming, Raymond Lance, Christopher L Corless, etc.

Urol Oncol. 2016 Jan;34(1):4.e11-7.

PMID: 26362343

1

Possible Involvement of Calcineurin, Protein Kinase C, and Src-family Kinases in Angiotensin II-induced Tyrosine Phosphorylation of p130cas in Rat Cardiac Muscle

H Nishio, H Tsuji, A Tamura, K Suzuki

Leg Med (Tokyo). 1999 Apr;1(2):105-10.

PMID: 12935502

1

Src and Cas Are Essentially but Differentially Involved in Angiotensin II-stimulated Migration of Vascular Smooth Muscle Cells via Extracellular Signal-Regulated Kinase 1/2 and c-Jun NH2-terminal Kinase Activation

Moe Kyaw, Masanori Yoshizumi, Koichiro Tsuchiya, Shoji Kagami, Yuki Izawa, Yoshiko Fujita, Nermin Ali, Yasuhisa Kanematsu, Kazunori Toida, Kazunori Ishimura, Toshiaki Tamaki

Mol Pharmacol. 2004 Apr;65(4):832-41.

PMID: 15044612

1

Tyrosine Dephosphorylation, but Not Phosphorylation, of p130Cas Is Dependent on Integrin Alpha IIb Beta 3-mediated Aggregation in Platelets: Implication of p130Cas Involvement in Pathways Unrelated to Cytoskeletal Reorganization

T Ohmori, Y Yatomi, K Inoue, K Satoh, Y Ozaki

Biochemistry. 2000 May 16;39(19):5797-807.

PMID: 10801330

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