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SRPIN340

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For Research Use Only | Not For Clinical Use
CATAP218156968
CAS218156-96-8
Structure
MDL NumberMFCD00116244
Molecular Weight349.35
InChI KeyDWFGGOFPIISJIT-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Challenges to Congenital Genetic Disorders With "RNA-targeting" Chemical Compounds

Yasushi Ogawa, Masatoshi Hagiwara

Pharmacol Ther. 2012 Jun;134(3):298-305.

PMID: 22342810

1

Specific Inhibition of serine/arginine-rich Protein Kinase Attenuates Choroidal Neovascularization

Zhenyu Dong, Kousuke Noda, Atsuhiro Kanda, Junichi Fukuhara, Ryo Ando, Miyuki Murata, Wataru Saito, Masatoshi Hagiwara, Susumu Ishida

Mol Vis. 2013;19:536-43.

PMID: 23559848

1

SRPIN340 Protects Heart Muscle From Oxidative Damage via SRPK1/2 Inhibition-Mediated AKT Activation

Jian Huang, Yaqun Zhou, Xiaoyu Xue, Liudan Jiang, Jimin Du, Yingyu Cui, Hong Zhao

Biochem Biophys Res Commun. 2019 Feb 26;510(1):97-103.

PMID: 30661787

1

SRPKIN-1: A Covalent SRPK1/2 Inhibitor That Potently Converts VEGF From Pro-angiogenic to Anti-angiogenic Isoform

John M Hatcher, Guowei Wu, Chuyue Zeng, Jie Zhu, Fan Meng, Sherrina Patel, Wenqiu Wang, Scott B Ficarro, Alan L Leggett, Chelsea E Powell, Jarrod A Marto, Kang Zhang, Jacky Chi Ki Ngo, Xiang-Dong Fu, Tinghu Zhang, etc.

Cell Chem Biol. 2018 Apr 19;25(4):460-470.e6.

PMID: 29478907

1

Trifluoromethyl Arylamides With Antileukemia Effect and Intracellular Inhibitory Activity Over serine/arginine-rich Protein Kinases (SRPKs)

Raoni Pais Siqueira, Marcus Vinícius de Andrade Barros, Éverton de Almeida Alves Barbosa, Thiago Souza Onofre, Victor Hugo Sousa Gonçalves, Higor Sette Pereira, Abelardo Silva Júnior, Leandro Licursi de Oliveira, etc.

Eur J Med Chem. 2017 Jul 7;134:97-109.

PMID: 28407594

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