0

Staurosporine, N-Benzoyl

INQUIRY Add to cart
For Research Use Only | Not For Clinical Use
CATAP120685112
CAS120685-11-2
Structure
Molecular Weight570.64
DescriptionA cell-permeable Staurosporine derivative that displays antitumor properties.
SolubilityDMSO: 6 mg/mL
Assay≥98% (HPLC)
Colortan
Formsolid; protect from light
Size1MG
Storage Conditions-20C
1

A Phase I Trial of Daily Oral 4'- N -Benzoyl-Staurosporine in Combination With Protracted Continuous Infusion 5-fluorouracil in Patients With Advanced Solid Malignancies

Joseph P Eder Jr, Rocio Garcia-Carbonero, Jeffrey W Clark, Jeffrey G Supko, Thomas A Puchalski, David P Ryan, Pamela Deluca, Antoinette Wozniak, Angela Campbell, John Rothermel, Patricia LoRusso

Invest New Drugs. 2004 Apr;22(2):139-50.

PMID: 14739662

1

Antitumor Activity of the New Selective Protein Kinase C Inhibitor 4'-N-benzoyl Staurosporine on Murine and Human Tumor Models

Y Ikegami, S Yano, K Nakao, F Fujita, M Fujita, Y Sakamoto, N Murata, K Isowa

Arzneimittelforschung. 1995 Nov;45(11):1225-30.

PMID: 8929245

1

Effects of the New Selective Protein Kinase C Inhibitor 4'-N-benzoyl Staurosporine on Cell Cycle Distribution and Growth Inhibition in Human Small Cell Lung Cancer Cells

Y Ikegami, S Yano, K Nakao

Arzneimittelforschung. 1996 Feb;46(2):201-4.

PMID: 8720314

1

Phase I Study of PKC412 (N-benzoyl-staurosporine), a Novel Oral Protein Kinase C Inhibitor, Combined With Gemcitabine and Cisplatin in Patients With Non-Small-Cell Lung Cancer

C Monnerat, R Henriksson, T Le Chevalier, S Novello, P Berthaud, S Faivre, E Raymond

Ann Oncol. 2004 Feb;15(2):316-23.

PMID: 14760128

1

Spotlight on Midostaurin in the Treatment of FLT3-mutated Acute Myeloid Leukemia and Systemic Mastocytosis: Design, Development, and Potential Place in Therapy

Ellen Weisberg, Martin Sattler, Paul W Manley, James D Griffin

Onco Targets Ther. 2017 Dec 29;11:175-182.

PMID: 29343975

  • Verification code
Contact Us

Send Us a Request

What is your specific need? We will do everything we can to meet your expectations.
Online Inquiry

Online Inquiry

For any inquiry, question or recommendation, please call: or fill out the following form.

  • Verification code

Head Office

  • Tel:
  • Email:

Follow us on

qrcode