0

STF-083010

INQUIRY Add to cart
For Research Use Only | Not For Clinical Use
CATAP307543711
CAS307543-71-1
MDL NumberMFCD02332975
Molecular Weight317.38
InChI KeyTVIVJHZHPKNDAQ-MHWRWJLKSA-N
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL (clear solution)
Assay≥98% (HPLC)
Colorlight yellow to yellow-green
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

A Novel Chemical, STF-083010, Reverses Tamoxifen-Related Drug Resistance in Breast Cancer by Inhibiting IRE1/XBP1

Jie Ming, Shengnan Ruan, Mengyi Wang, Dan Ye, Ningning Fan, Qingyu Meng, Bo Tian, Tao Huang

Oncotarget. 2015 Dec 1;6(38):40692-703.

PMID: 26517687

1

Identification of an Ire1alpha Endonuclease Specific Inhibitor With Cytotoxic Activity Against Human Multiple Myeloma

Ioanna Papandreou, Nicholas C Denko, Michael Olson, Heleen Van Melckebeke, Sofie Lust, Arvin Tam, David E Solow-Cordero, Donna M Bouley, Fritz Offner, Maho Niwa, Albert C Koong

Blood. 2011 Jan 27;117(4):1311-4.

PMID: 21081713

1

Inositol-requiring Enzyme 1 Alpha Endoribonuclease Specific Inhibitor STF-083010 Protects the Liver From Thioacetamide-Induced Oxidative Stress, Inflammation and Injury by Triggering Hepatocyte Autophagy

Feng Zhan, Guoping Zhao, Xu Li, Shikun Yang, Wenjie Yang, Shun Zhou, Feng Zhang

Int Immunopharmacol. 2019 Aug;73:261-269.

PMID: 31121416

1

IRE1α Inhibition Decreased TXNIP/NLRP3 Inflammasome Activation Through miR-17-5p After Neonatal Hypoxic-Ischemic Brain Injury in Rats

Di Chen, Brandon J Dixon, Desislava M Doycheva, Bo Li, Yang Zhang, Qin Hu, Yue He, Zongduo Guo, Derek Nowrangi, Jerry Flores, Valery Filippov, John H Zhang, Jiping Tang

J Neuroinflammation. 2018 Feb 2;15(1):32.

PMID: 29394934

1

STF-083010, an Inhibitor of XBP1 Splicing, Attenuates Acute Renal Failure in Rats by Suppressing Endoplasmic Reticulum Stress-Induced Apoptosis and Inflammation

Lei Liu, Lu Xu, Shaoqing Zhang, Dong Wang, Guoxia Dong, Hanwen Chen, Xinjian Li, Chi Shu, Rong Wang

Exp Anim. 2018 Jul 30;67(3):373-382.

PMID: 29695649

  • Verification code
Contact Us

Send Us a Request

What is your specific need? We will do everything we can to meet your expectations.
Online Inquiry

Online Inquiry

For any inquiry, question or recommendation, please call: or fill out the following form.

  • Verification code

Head Office

  • Tel:
  • Email:

Follow us on

qrcode