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STF-62247

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For Research Use Only | Not For Clinical Use
CATAP315702999
CAS315702-99-9
Structure
MDL NumberMFCD01121974
Molecular Weight267.35
InChI KeyKATNUHQNJGNLPW-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: soluble 26 mg/mL; H2O: insoluble
Assay≥98% (HPLC)
Formsolid
Size5MG
Storage Conditionsroom temp
1

Loperamide, Pimozide, and STF-62247 Trigger Autophagy-Dependent Cell Death in Glioblastoma Cells

Svenja Zielke, Nina Meyer, Muriel Mari, Khalil Abou-El-Ardat, Fulvio Reggiori, Sjoerd J L van Wijk, Donat Kögel, Simone Fulda

Cell Death Dis. 2018 Sep 24;9(10):994.

PMID: 30250198

1

Quantitative Proteomics to Study a Small Molecule Targeting the Loss of Von Hippel-Lindau in Renal Cell Carcinomas

Nadia Bouhamdani, Andrew Joy, David Barnett, Kevin Cormier, Daniel Léger, Ian C Chute, Simon Lamarre, Rodney Ouellette, Sandra Turcotte

Int J Cancer. 2017 Aug 15;141(4):778-790.

PMID: 28486780

1

STF-62247 Accumulates in Lysosomes and Blocks Late Stages of Autophagy to Selectively Target Von Hippel-Lindau-inactivated Cells

Nadia Bouhamdani, Dominique Comeau, Kevin Cormier, Sandra Turcotte

Am J Physiol Cell Physiol. 2019 May 1;316(5):C605-C620.

PMID: 30758995

1

STF-62247 and Pimozide Induce Autophagy and Autophagic Cell Death in Mouse Embryonic Fibroblasts

Maximilian N Kinzler, Svenja Zielke, Simon Kardo, Nina Meyer, Donat Kögel, Sjoerd J L van Wijk, Simone Fulda

Sci Rep. 2020 Jan 20;10(1):687.

PMID: 31959760

1

The Small Molecule STF-62247 Induces Apoptotic and Autophagic Cell Death in Leukemic Cells

Tomohiro Kozako, Keisuke Sato, Yuichiro Uchida, Naho Kato, Akiyoshi Aikawa, Kentaro Ogata, Hidetoshi Kamimura, Haruna Uemura, Makoto Yoshimitsu, Kenji Ishitsuka, Yasuki Higaki, Hiroaki Tanaka, Shin-Ichiro Honda, etc.

Oncotarget. 2018 Jun 12;9(45):27645-27655.

PMID: 29963226

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