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SU5614

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For Research Use Only | Not For Clinical Use
CATAP1055412479
CAS1055412-47-9
Structure
MDL NumberMFCD08443928
Molecular Weight272.73
InChI KeyXLBQNZICMYZIQT-GHXNOFRVSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥20 mg/mL
Assay≥98% (HPLC)
Colororange
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Effects of the Protein Tyrosine Kinase Inhibitor, SU5614, on Leukemic and Normal Stem Cells

Natalia Arseni, Farid Ahmed, Wolfgang Hiddemann, Christian Buske, Michaela Feuring-Buske

Haematologica. 2005 Nov;90(11):1577-8.

PMID: 16266907

1

FMS-like Tyrosine Kinase 3-internal Tandem Duplication Tyrosine Kinase Inhibitors Display a Nonoverlapping Profile of Resistance Mutations in Vitro

Nikolas von Bubnoff, Richard A Engh, Espen Aberg, Jana Sänger, Christian Peschel, Justus Duyster

Cancer Res. 2009 Apr 1;69(7):3032-41.

PMID: 19318574

1

SU5416 and SU5614 Inhibit Kinase Activity of Wild-Type and Mutant FLT3 Receptor Tyrosine Kinase

Kevin W H Yee, Anne Marie O'Farrell, Beverly D Smolich, Julie M Cherrington, Gerald McMahon, Cecily L Wait, Laura S McGreevey, Diana J Griffith, Michael C Heinrich

Blood. 2002 Oct 15;100(8):2941-9.

PMID: 12351406

1

The Protein Tyrosine Kinase Inhibitor SU5614 Inhibits FLT3 and Induces Growth Arrest and Apoptosis in AML-derived Cell Lines Expressing a Constitutively Activated FLT3

Karsten Spiekermann, Ralf J Dirschinger, Ruth Schwab, Ksenia Bagrintseva, Florian Faber, Christian Buske, Susanne Schnittger, Louise M Kelly, D Gary Gilliland, Wolfgang Hiddemann

Blood. 2003 Feb 15;101(4):1494-504.

PMID: 12406902

1

The Protein Tyrosine Kinase Inhibitor SU5614 Inhibits VEGF-induced Endothelial Cell Sprouting and Induces Growth Arrest and Apoptosis by Inhibition of C-Kit in AML Cells

Karsten Spiekermann, Florian Faber, Robert Voswinckel, Wolfgang Hiddemann

Exp Hematol. 2002 Jul;30(7):767-73.

PMID: 12135675

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