CAS 59864-04-9 Sulindac sulfone - Analytical Products / Alfa Chemistry

CAT	AP59864049
CAS	59864-04-9
Structure
MDL Number	MFCD01317811
Molecular Weight	372.41
InChI Key	MVGSNCBCUWPVDA-RQZCQDPDSA-N

Description	≥94% (HPLC), (solid or powder)
Solubility	DMSO: >25 mg/mL; ethanol: 3 mg/mL (warm); acetone: 5 mg (plus 0.1 ml)
Assay	≥94% (HPLC)
Color	, Light Yellow to Dark Yellow
Form	(solid or powder)
Size	5MG, 25MG

1

Sulfone Metabolite of Sulindac Inhibits Mammary Carcinogenesis

H J Thompson, C Jiang, J Lu, R G Mehta, G A Piazza, N S Paranka, R Pamukcu, D J Ahnen

Cancer Res. 1997 Jan 15;57(2):267-71.

PMID: 9000566

1

Sulindac Sulfide, but Not Sulindac Sulfone, Inhibits Colorectal Cancer Growth

C S Williams, A P Goldman, H Sheng, J D Morrow, R N DuBois

Neoplasia. 1999 Jun;1(2):170-6.

PMID: 10933052

1

Sulindac Sulfone Induces a Decrease of Beta-Catenin in HNSCC

Alexander Sauter, Hannah Soulsby, Karl Hormann, Ramin Naim

Anticancer Res. 2010 Feb;30(2):339-43.

PMID: 20332437

1

Sulindac Sulfone Inhibits the mTORC1 Pathway in Colon Cancer Cells by Directly Targeting Voltage-Dependent Anion Channel 1 and 2

Yuichi Aono, Mano Horinaka, Yosuke Iizumi, Motoki Watanabe, Tomoyuki Taniguchi, Shusuke Yasuda, Toshiyuki Sakai

Biochem Biophys Res Commun. 2018 Nov 10;505(4):1203-1210.

PMID: 30327144

1

Sulindac Sulfone Modulates Beta-Catenin in Human Cholesteatoma Cell Culture

Alexander Sauter, Rubina Matharu, Theresa Braun, Johannes Schultz, Haneen Sadick, Karl Hormann, Ramin Naim

Arch Med Res. 2007 May;38(4):367-71.

PMID: 17416281