α-Synuclein A53T human - Analytical Products / Alfa Chemistry

CAT	IAR4248204
MDL Number	MFCD06411759

Description	recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder
Assay	≥90% (SDS-PAGE)
Form	lyophilized powder
Size	500μG
Storage Conditions	−20°C

1

A53T Human α-synuclein Overexpression in Transgenic Mice Induces Pervasive Mitochondria Macroautophagy Defects Preceding Dopamine Neuron Degeneration

Linan Chen, Zhiguo Xie, Susie Turkson, Xiaoxi Zhuang

J Neurosci. 2015 Jan 21;35(3):890-905.

PMID: 25609609

1

Multiple System Atrophy Prions Retain Strain Specificity After Serial Propagation in Two Different Tg(SNCA*A53T) Mouse Lines

Amanda L Woerman, Abby Oehler, Sabeen A Kazmi, Jisoo Lee, Glenda M Halliday, Lefkos T Middleton, Steve M Gentleman, Daniel A Mordes, Salvatore Spina, Lea T Grinberg, Steven H Olson, Stanley B Prusiner

Acta Neuropathol. 2019 Mar;137(3):437-454.

PMID: 30690664

1

Mutant A53T α-Synuclein Improves Rotarod Performance Before Motor Deficits and Affects Metabolic Pathways

Patrícia S Guerreiro, Joana E Coelho, Inês Sousa-Lima, Paula Macedo, Luísa V Lopes, Tiago F Outeiro, Teresa F Pais

Neuromolecular Med. 2017 Mar;19(1):113-121.

PMID: 27535567

1

Neuronal Alpha-Synucleinopathy With Severe Movement Disorder in Mice Expressing A53T Human Alpha-Synuclein

Benoit I Giasson, John E Duda, Shawn M Quinn, Bin Zhang, John Q Trojanowski, Virginia M-Y Lee

Neuron. 2002 May 16;34(4):521-33.

PMID: 12062037

1

Studies of Protein Aggregation in A53T α-synuclein Transgenic, Tg2576 Transgenic, and P246L presenilin-1 Knock-In Cross Bred Mice

Kristel L Emmer, Jason P Covy, Benoit I Giasson

Neurosci Lett. 2012 Jan 24;507(2):137-42.

PMID: 22188655

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