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Syrosingopine

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For Research Use Only | Not For Clinical Use
CATAP84366
CAS84-36-6
Structure
Molecular Weight666.71
Description≥95% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥95% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal With Metformin Due to NAD+ Depletion in Cancer Cells

Don Benjamin, Dimitri Robay, Sravanth K Hindupur, Jens Pohlmann, Marco Colombi, Mahmoud Y El-Shemerly, Sauveur-Michel Maira, Christoph Moroni, Heidi A Lane, Michael N Hall

Cell Rep. 2018 Dec 11;25(11):3047-3058.e4.

PMID: 30540938

1

Effects of Amnesic Doses of Reserpine or Syrosingopine on Mouse Brain Acetylcholine Levels

T Palfai, L Wichlinski, H A Brown, O M Brown

Pharmacol Biochem Behav. 1986 May;24(5):1457-9.

PMID: 2873591

1

Prolactin Secretion During Reserpine and Syrosingopine Treatment

E Camanni, E Strumia, P Portaleone, G M Molinatti

Eur J Clin Pharmacol. 1981;20(5):347-9.

PMID: 6116608

1

Selective Depleting Effect of Syrosingopine on Brain Catecholamine Levels With Relation to Morphine Analgesia in the Rat

T Furukawa, T Sano, Y Kohno, M Koga, N Nagasaki

Pharmacol Biochem Behav. 1976 Apr;4(4):419-25.

PMID: 6976

1

Syrosingopine Sensitizes Cancer Cells to Killing by Metformin

Don Benjamin, Marco Colombi, Sravanth K Hindupur, Charles Betz, Heidi A Lane, Mahmoud Y M El-Shemerly, Min Lu, Luca Quagliata, Luigi Terracciano, Suzette Moes, Timothy Sharpe, Aleksandra Wodnar-Filipowicz, etc.

Sci Adv. 2016 Dec 23;2(12):e1601756.

PMID: 28028542

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