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SYUIQ-5

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For Research Use Only | Not For Clinical Use
CATAP188630479
CAS188630-47-9
MDL NumberMFCD17215940
Molecular Weight318.42
InChI KeyCTDCVGDSVHUYMA-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥20 mg/mL
Assay≥98% (HPLC)
Coloryellow
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

[A G-quadruplex Ligand SYUIQ-5 Induces Autophagy by Inhibiting the Akt-FOXO3a Pathway in Nasopharyngeal Cancer Cells]

Wen-Jun Zhou, Rong Deng, Gong-Kan Feng, Xiao-Feng Zhu

Ai Zheng. 2009 Oct;28(10):1049-53.

PMID: 19799812

1

Biotransformation and Pharmacokinetics of the Novel Anticancer Drug, SYUIQ-5, in the Rat

Qi-Biao Su, Fan He, Xue-Ding Wang, Su Guan, Zhi-Yong Xie, Lai-You Wang, Yu-Jing Lu, Lian-Quan Gu, Zhi-Shu Huang, Xiao Chen, Min Huang, Shu-Feng Zhou

Invest New Drugs. 2008 Apr;26(2):119-37.

PMID: 17922078

1

G-quadruplex Ligand SYUIQ-5 Induces Autophagy by Telomere Damage and TRF2 Delocalization in Cancer Cells

Wen-Jun Zhou, Rong Deng, Xiao-Yue Zhang, Gong-Kan Feng, Lian-Quan Gu, Xiao-Feng Zhu

Mol Cancer Ther. 2009 Dec;8(12):3203-13.

PMID: 19996277

1

High Performance Liquid Chromatography With Ultraviolet Detection for the Determination of SYUIQ-5, a Novel Telomerase Inhibitor for Cancer Therapy: Application to an Enzyme Kinetic Study in Rat Liver Microsomes

Qi-Biao Su, Fan He, Su Guan, Yu-Jing Lu, Lian-Quan Gu, Zhi-Shu Huang, Xiao Chen, Min Huang, Chun-Guang Li, Balram Chowbay, Shu-Feng Zhou

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jul 1;854(1-2):332-7.

PMID: 17449337

1

Inhibition of Myc Promoter and Telomerase Activity and Induction of Delayed Apoptosis by SYUIQ-5, a Novel G-quadruplex Interactive Agent in Leukemia Cells

J-N Liu, R Deng, J-F Guo, J-M Zhou, G-K Feng, Z-S Huang, L-Q Gu, Y-X Zeng, X-F Zhu

Leukemia. 2007 Jun;21(6):1300-2.

PMID: 17392822

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