Talnetant

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For Research Use Only | Not For Clinical Use

CAT	AP174636329
CAS	174636-32-9
MDL Number	MFCD00944075
Molecular Weight	382.45
InChI Key	BIAVGWDGIJKWRM-FQEVSTJZSA-N

Description	≥98% (HPLC)
Solubility	DMSO: 25 mg/mL, clear
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	2-8°C

Augmentation of Antipsychotic-Induced Neurochemical Changes by the NK3 Receptor Antagonist Talnetant (SB-223412)

Raúl de la Flor, Lee A Dawson

Neuropharmacology. 2009 Feb;56(2):342-9.

PMID: 18822303

Development of Novel NK3 Receptor Antagonists With Reduced Environmental Impact

Koki Yamamoto, Shiho Okazaki, Hiroaki Ohno, Fuko Matsuda, Satoshi Ohkura, Kei-Ichiro Maeda, Nobutaka Fujii, Shinya Oishi

Bioorg Med Chem. 2016 Aug 15;24(16):3494-500.

PMID: 27298001

Gateways to Clinical Trials

M Bayes, X Rabasseda, J R Prous

Methods Find Exp Clin Pharmacol. 2002 Apr;24(3):159-84.

PMID: 12087878

Me-talnetant and Osanetant Interact Within Overlapping but Not Identical Binding Pockets in the Human Tachykinin Neurokinin 3 Receptor Transmembrane Domains

Pari Malherbe, Caterina Bissantz, Anne Marcuz, Claudia Kratzeisen, Marie-Thérèse Zenner, Joseph G Wettstein, Hasane Ratni, Claus Riemer, Will Spooren

Mol Pharmacol. 2008 Jun;73(6):1736-50.

PMID: 18308898

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