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TAS-301

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For Research Use Only | Not For Clinical Use
CATAP193620698
CAS193620-69-8
Structure
MDL NumberMFCD05865245
Molecular Weight357.40
InChI KeyKUEYYIJXBRWZIB-UHFFFAOYSA-N
Description≥95% (HPLC), solid
SolubilityDMSO: 40 mg/mL
Assay≥95% (HPLC)
Formsolid
Size10MG
1

Improvement of Solubility and Oral Bioavailability of a Poorly Water-Soluble Drug, TAS-301, by Its Melt-Adsorption on a Porous Calcium Silicate

Masahiro Kinoshita, Kazuhiko Baba, Atushi Nagayasu, Kanoo Yamabe, Takashi Shimooka, Yoh'ichiro Takeichi, Mami Azuma, Hitoshi Houchi, Kazuo Minakuchi

J Pharm Sci. 2002 Feb;91(2):362-70.

PMID: 11835196

1

Inhibitory Effect of TAS-301, a New Synthesized Constrictive Remodeling Regulator, on Renarrowing After Balloon Overstretch Injury of Porcine Coronary Artery

E Sasaki, Y Tanahashi, Y Yamasaki, N Oda, Y Nozawa, H Terakawa, K Miyoshi, Y Muranaka, H Miyake, N Matsuura

J Pharmacol Exp Ther. 2000 Dec;295(3):1043-50.

PMID: 11082439

1

TAS-301 Blocks Receptor-Operated Calcium Influx and Inhibits Rat Vascular Smooth Muscle Cell Proliferation Induced by Basic Fibroblast Growth Factor and Platelet-Derived Growth Factor

E Sasaki, Y Nozawa, K Miyoshi, A Kanda, Y Yamasaki, H Miyake, N Matsuura

Jpn J Pharmacol. 2000 Nov;84(3):252-8.

PMID: 11138725

1

Tas-301, a New Synthetic Inhibitor of Neointimal Thickening After Balloon Injury, Inhibits Calcium-Dependent Signal Transduction and Cytoskeletal Reorganization

E Sasaki, K Miyoshi, Y Nozawa, A Kanda, K Nakano, Y Yamasaki, H Miyake, N Matsuura

Pharmacology. 2001 Jul;63(1):17-27.

PMID: 11408828

1

TAS-301, an Inhibitor of Smooth Muscle Cell Migration and Proliferation, Inhibits Intimal Thickening After Balloon Injury to Rat Carotid Arteries

Y Muranaka, Y Yamasaki, Y Nozawa, H Terakawa, Y Tanahashi, N Oda, A Satoh, T Asao, H Miyake, N Matsuura

J Pharmacol Exp Ther. 1998 Jun;285(3):1280-6.

PMID: 9618434

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