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Tautomycin from Streptomyces spiroverticillatus

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For Research Use Only | Not For Clinical Use
CATAP109946352
CAS109946-35-2
Structure
Molecular Weight766.95
InChI KeyRFCWHQNNCOJYTR-QKIDKDKQSA-N
REAXYS Number3583132
Description≥90% (HPLC)
Assay≥90% (HPLC)
Size50μG
Storage Conditions−20°C
1

Antifungal Activity of Tautomycin and Related Compounds Against Sclerotinia Sclerotiorum

Xiaolong Chen, Xiaohui Zhu, Yicheng Ding, Yinchu Shen

J Antibiot (Tokyo). 2011 Aug;64(8):563-9.

PMID: 21772304

1

Characterization of the Tautomycin Biosynthetic Gene Cluster From Streptomyces Spiroverticillatus Unveiling New Insights Into Dialkylmaleic Anhydride and Polyketide Biosynthesis

Wenli Li, Jianhua Ju, Scott R Rajski, Hiroyuki Osada, Ben Shen

J Biol Chem. 2008 Oct 17;283(42):28607-17.

PMID: 18708355

1

Tautomycetin and Tautomycin Suppress the Growth of Medullary Thyroid Cancer Cells via Inhibition of Glycogen Synthase kinase-3beta

Joel T Adler, Mackenzie Cook, Yinggang Luo, Susan C Pitt, Jianhua Ju, Wenli Li, Ben Shen, Muthusamy Kunnimalaiyaan, Herbert Chen

Mol Cancer Ther. 2009 Apr;8(4):914-20.

PMID: 19372564

1

Tautomycin: An Inhibitor of Protein Phosphatases 1 and 2A but Not a Tumor Promoter on Mouse Skin and in Rat Glandular Stomach

M Suganuma, S Okabe, E Sueoka, R Nishiwaki, A Komori, N Uda, K Isono, H Fujiki

J Cancer Res Clin Oncol. 1995;121(9-10):621-7.

PMID: 7559747

1

Utilization of the Methoxymalonyl-Acyl Carrier Protein Biosynthesis Locus for Cloning of the Tautomycin Biosynthetic Gene Cluster From Streptomyces Spiroverticillatus

Wenli Li, Jianhua Ju, Hiroyuki Osada, Ben Shen

J Bacteriol. 2006 Jun;188(11):4148-52.

PMID: 16707708

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