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TC-2153

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For Research Use Only | Not For Clinical Use
CATAP1381769238
CAS1381769-23-8
Molecular Weight355.89
Description≥95% (HPLC)
SolubilityDMSO: 5 mg/mL, clear
Assay≥95% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

[Comparison of Behavioral Effects of Fluoxetine, Imipramine and New Psychotropic Drug TC-2153 on Mice With Hereditary Predisposition to Catalepsy]

E A Kulikova, M A Tikhonova, K P Volcho, T M Khomenko, N F Salakhutdinov, A V Kulikov, N K Popova

Zh Vyssh Nerv Deiat Im I P Pavlova. Jan-Feb 2015;65(1):105-12.

PMID: 25966577

1

A New Synthetic Varacin Analogue, 8-(trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine Hydrochloride (TC-2153), Decreased Hereditary Catalepsy and Increased the BDNF Gene Expression in the Hippocampus in Mice

Alexander V Kulikov, Maria A Tikhonova, Elizabeth A Kulikova, Konstantin P Volcho, Tatyana M Khomenko, Nariman F Salakhutdinov, Nina K Popova

Psychopharmacology (Berl). 2012 Jun;221(3):469-78.

PMID: 22127556

1

Effects of Fluoxetine and Potential Antidepressant 8-Trifluoromethyl 1,2,3,4,5-Benzopentathiepin-6-Amine Hydrochloride (TC-2153) on Behavior of Danio Rerio Fish in the Novel Tank Test and Brain Content of Biogenic Amines and Their Metabolites

N A Sinyakova, E A Kulikova, N A Englevskii, A V Kulikov

Bull Exp Biol Med. 2018 Mar;164(5):620-623.

PMID: 29577201

1

Inhibitor of Striatal-Enriched Protein Tyrosine Phosphatase, 8-(Trifluoromethyl)-1,2,3,4,5-Benzopentathiepin-6-Amine Hydrochloride (TC-2153), Produces Antidepressant-Like Effect and Decreases Functional Activity and Protein Level of 5-HT

E A Kulikova, N V Khotskin, N B Illarionova, I E Sorokin, E Y Bazhenova, E M Kondaurova, K P Volcho, T M Khomenko, N F Salakhutdinov, E Ponimaskin, V S Naumenko, A V Kulikov

Neuroscience. 2018 Dec 1;394:220-231.

PMID: 30367948

1

STEP Inhibition Reverses Behavioral, Electrophysiologic, and Synaptic Abnormalities in Fmr1 KO Mice

Manavi Chatterjee, Pradeep K Kurup, Camilla J Lundbye, Anna Karina Hugger Toft, Jeemin Kwon, Jessie Benedict, Marija Kamceva, Tue G Banke, Paul J Lombroso

Neuropharmacology. 2018 Jan;128:43-53.

PMID: 28943283

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