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TGN-020

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For Research Use Only | Not For Clinical Use
CATAP51987996
CAS51987-99-6
Structure
MDL NumberMFCD00708771
Molecular Weight206.22
InChI KeyAGEGZHOPKZFKBP-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥8 mg/mL
Assay≥98% (HPLC)
Colorwhite to tan
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Correlation of TGN-020 With the Analgesic Effects via ERK Pathway Activation After Chronic Constriction Injury

Liang Zhao, Dan Li, Nan Liu, Lu Liu, Zhuo Zhang, Chao Gao, Hitoshi Kawano, Fang-Yuan Zhou, Hong-Peng Li

Mol Pain. Jan-Dec 2018;14:1744806918796057.

PMID: 30152258

1

Effects of an Aquaporin 4 Inhibitor, TGN-020, on Murine Diabetic Retina

Shou Oosuka, Teruyo Kida, Hidehiro Oku, Taeko Horie, Seita Morishita, Masanori Fukumoto, Takaki Sato, Tsunehiko Ikeda

Int J Mol Sci. 2020 Mar 27;21(7):2324.

PMID: 32230876

1

Inhibitors of Mammalian Aquaporin Water Channels

Mohammed Abir-Awan, Philip Kitchen, Mootaz M Salman, Matthew T Conner, Alex C Conner, Roslyn M Bill

Int J Mol Sci. 2019 Mar 29;20(7):1589.

PMID: 30934923

1

Pretreatment With a Novel Aquaporin 4 Inhibitor, TGN-020, Significantly Reduces Ischemic Cerebral Edema

Hironaka Igarashi, Vincent J Huber, Mika Tsujita, Tsutomu Nakada

Neurol Sci. 2011 Feb;32(1):113-6.

PMID: 20924629

1

TGN-020 Alleviates Edema and Inhibits Astrocyte Activation and Glial Scar Formation After Spinal Cord Compression Injury in Rats

Jian Li, Zhiqiang Jia, Wen Xu, Weidong Guo, Mingchao Zhang, Jing Bi, Yang Cao, Zhongkai Fan, Gang Li

Life Sci. 2019 Apr 1;222:148-157.

PMID: 30851336

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